Steroidogenic Response of Adrenal Tissues After Administration of ACTH to Dogs With Hypercortisolemia
January 2001
in “
Journal of the American Veterinary Medical Association
”
Studysummary This study found that adrenal sex hormone levels were elevated in neutered dogs with hypercortisolemia, except for testosterone, highlighting the importance of ruling out hypercortisolemia when diagnosing adrenal hyperplasia syndrome. Our plain-language summary of this paper — not a Tressless recommendation.
The study evaluated adrenal sex hormone concentrations in 11 neutered dogs with hypercortisolemia by measuring serum samples before and after ACTH administration. It found that concentrations of one or more adrenal sex hormones were significantly higher than reference values, except for testosterone, which remained within normal ranges. The study concluded that it was important to rule out hypercortisolemia before using adrenal sex hormone concentrations to diagnose adrenal hyperplasia syndrome (alopecia X) in dogs.
