This study formulated and evaluated a Hibiscus rosa-sinensis herbal gel, identifying a 20% concentration as superior in physical properties, suggesting its potential as an alternative drug delivery system.
127 citations
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June 2006 in “International Journal of Pharmaceutics” This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.
29 citations
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September 2024 in “AAPS PharmSciTech” This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the researchers observed that extracts from rosemary (including essential oil, hydrolate, and alcoholic extract) significantly promoted hair growth in male mice, surpassing the effects of the commercial drug minoxidil.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers observed that rosemary plant extracts (essential oil, hydrolate, and alcoholic extract) promoted hair growth in male mice more than a distilled water control and even performed better than 5% minoxidil over five weeks.
2 citations
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January 2018 in “International Journal of ChemTech Research” This study used phytochemical screening and FTIR spectroscopy with PCA to reveal slight chemical differences between two varieties of Eclipta alba, providing a method for their effective discrimination.
5 citations
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August 2018 This paper highlights the growing scientific interest in plant extracts for cosmetics due to their potential benefits, including antioxidant, antimicrobial, and protective properties, while emphasizing the need for quality and safety assessment to mitigate possible adverse reactions.
3 citations
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July 2019 in “International journal of scientific research in science and technology” This study found that a herbal gel containing fenugreek seed extract significantly promoted hair growth on mice after 30 days of topical application.
November 2025 in “Frontiers in Nutrition” Olive leaf extract may help reduce aging signs in postmenopausal women.
March 2024 in “Journal of Pharmaceutical and Sciences” This study investigated the phytochemical composition and antibacterial and antioxidant activities of Zaleya pentandra extracts, finding high total polyphenol and flavonoid content and significant antibacterial effects, particularly in acetone extract, which may be suitable for developing antibacterial agents.
4 citations
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July 2021 in “Armaghane Danesh” These plant extracts can kill some bacteria.
2 citations
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August 2019 in “Asian journal of pharmaceutical and clinical research” This study found that in female breast cancer patients, supplementation with 400 mg IND02 (Cinnamon bark extract) thrice daily during chemotherapy significantly reduced severe weight loss and hair loss compared to placebo, with the treatment being well-tolerated and safe.
November 2024 in “Indus journal of bioscience research.” In this animal study, funnel seed extract significantly reduced insulin and testosterone levels and increased ovulating hormones in rats with induced polycystic ovarian syndrome, suggesting potential hormone-regulating properties.
November 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This study evaluated herbal hair gels made with extracts of flax seed and curry leaves, finding that the formulations offered good texture, stability, and sensory appeal while promoting healthy hair and scalp without irritation, making them suitable for regular use.
1 citations
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January 2018 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that a herbal shampoo and solution were more effective than placebo in reducing hair loss and improving hair growth in participants with androgenetic alopecia and telogen effluvium.
44 citations
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March 2020 in “Antibiotics” The researchers reported that carnosic acid and carnosol, extracts from rosemary leaves, specifically inhibit S. aureus virulence expression, suggesting potential topical treatments for atopic dermatitis flares.
19 citations
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January 2009 in “Journal of Young Pharmacists” This study found that the alcoholic extract of Eclipta alba exhibited dose-dependent antianaphylactic effects in animal models, possibly due to membrane stabilization and reduced histamine release.
4 citations
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September 2020 in “Andrologia” This study found that Origanum vulgare extract improved testicular structure and function in mice against finasteride-induced damage by enhancing antioxidant defense and modulating gene expression related to apoptosis.
May 2024 in “International Journal For Multidisciplinary Research” The study developed a hair cream using extracts from plants like Hibiscus rosa sinensis and Nigella sativa, reporting that it may protect the scalp and hair by providing antimicrobial effects, promoting hair growth, and preventing hair fall and graying.
December 2023 in “International Journal of Science and Research (IJSR)” This review article reports that many herbal drugs show potential for treating alopecia effectively and with fewer side effects compared to synthetic drugs, addressing a common issue among urban residents due to stress and environmental factors.
25 citations
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January 2013 in “Journal of Industrial and Engineering Chemistry” This study found that cubosomal suspensions significantly enhanced the hair growth-promoting effects of Thuja orientalis, Polygonum multiflorum Thunberg, and Espinosilla extracts in a mouse model, making them as effective as Minoxidil.
1 citations
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October 2021 in “Veterinary World” This study reported that a mixture of Elaeis guineensis kernel oil, essential oil of Ocimum gratissimum, and sap of Jatropha multifida showed better wound healing properties in Girolando cattle with dermatophilosis compared to other treatments.
4 citations
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September 2022 in “Indian Journal of Pharmaceutical Education and Research” This study found that methanolic leaf extract of Plumbago zeylanica L. demonstrates strong thrombolytic and antioxidant activities and shows promise as a source of such agents.
February 2026 in “Journal of Sylva Indonesiana” This study found that the heartwood extract of Avicennia marina demonstrated strong antioxidant activity, with an IC50 value of 61.50 µg/mL, suggesting potential for development into supplements or topical applications targeting degenerative diseases related to oxidative stress.
January 2023 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” This study found that a mixed extract of N. jatamansi, O. basilicum, and C. sativus, particularly when extracted via steaming and ultrasonic methods, increased antioxidant content, stimulated melanin production for black hair, and promoted hair growth in mouse models, while maintaining high cell viability.
7 citations
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January 2019 in “Brazilian Journal of Pharmaceutical Sciences” This study found that Adiantum capillus-veneris extract exhibited significant antidepressant and anti-anxiety effects in rats, likely due to its antioxidant and anti-inflammatory properties.
2 citations
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February 2025 in “Applied Microbiology and Biotechnology” This study suggests that Isaria cicadae Miquel rice fermentation extract may enhance regenerative wound healing of hair follicles in mouse skin through the Hippo pathway mechanism.
This study investigated the effects of ethanol leaf extracts from Ziziphus jujuba and Eclipta alba on cognitive impairments in diabetic rats, finding significant improvements in learning and memory with these treatments, along with decreased blood glucose levels over 21 days.
July 2021 in “Research Square (Research Square)” In this study, the ethyl acetate extract of Semecarpus anacardium Linn leaves was reported to induce cytotoxicity in cancer cells, cause cell cycle arrest, and suppress tumor growth in mice.
June 2026 in “Research Square” This study evaluated an herbal emulgel formulation containing extracts from Wedelia chinensis and Cassytha filiformis for hair growth promotion in rats, finding that the combined formulation significantly increased hair growth compared to both individual extracts and the control group.