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The supplement highlighted advancements and challenges in plastic and reconstructive surgery, including the impact of smoking, chemotherapy, and new treatments like Tafluprost for hair loss.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Lyophilized platelet-rich plasma is beneficial and effective for various medical treatments, including tissue regeneration and hair regrowth.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

Experts advise using sunscreen and proper skin care before, during, and after procedures to speed healing, prevent complications, and reduce scarring.

Platelet lysate effectively promotes hair growth and improves hair thickness in people with androgenetic alopecia.

Botulinum toxins are safe for various medical and cosmetic uses, but more research is needed for long-term safety and effectiveness in hair growth treatments.

Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.

PRP helps skin heal, possibly through special cells called telocytes.

The hydrogel made of chitosan, HPMC, and insulin speeds up wound healing and could be a new dressing, especially for diabetics.

ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.

Fish collagen peptides can significantly promote hair growth.

Polymeric nanoparticles show promise for treating skin diseases.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.