An Overview of Anti-Inflammatory, Antioxidant, Anti-Cancer, Anti-Hyperlipidemic, Neuroprotective and Muscle Relaxant Effects of Natural Flavonoid, Apigenin; A Review

    January 2024 in “ Biological & clinical sciences research journal ”
    Muhammad Azeem, HAA KHARL, Saif Ullah Niazi, Nabeela Ameer, Farwa Fayyaz, Nurul Huda, Tabassum Zehra, Maryam Aftab
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    TLDR Apigenin, found in plants and vegetables, has many health benefits, including anti-inflammatory, antioxidant, and anticancer effects.
    Apigenin, a natural glycoside found in various plants and vegetables, has demonstrated significant anti-inflammatory, antioxidant, cardioprotective, neuroprotective, and anticancer properties, especially when combined with allopathic drugs. It is less toxic and non-mutagenic, making it effective against skeletal muscle sarcoplasmic reticulum disorders. Notably, apigenin promotes hair growth by inhibiting the TGF-B1 pathway. The review analyzed 355 research articles, with 34% focusing on anti-inflammatory effects, 15% on neuroprotective effects, and 10% on anticancer properties. Various formulations and characterization techniques have been explored to enhance its biological role.
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