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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.

Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.

A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.

Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

Stem cell therapies show promise for treating hair loss, but more research is needed to understand their safety and effectiveness.

Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

New materials help control stem cell growth and specialization for medical applications.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Narrowband UVB treatment increases certain gene expressions in psoriasis skin and improves symptoms.

Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

SVF-PRP therapy effectively reverses hair loss effects.

Fat stem cell particles help regrow hair.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.

PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.

Curcumin may help reverse aging by targeting specific genes.

Boiling and fermenting certain herbs can help hair grow by activating hair growth genes and pathways.

Platelet-rich plasma may improve healing and hair growth in cosmetic surgery but results vary.