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The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

LED light therapy is effective for skin and hair treatments but requires careful use to minimize risks.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Careful selection of mice by genetics and age, and controlled housing conditions improve the reliability of hair regrowth in wound healing tests.

Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.

Autologous stem cell therapy may effectively increase hair density in Androgenetic Alopecia.

Cellular and immunotherapies show promise for healing chronic wounds but need more research.

Fat transplants using a patient's own fat can rejuvenate and repair tissues effectively.

Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.

Nanofat shows promise for facial rejuvenation and treating skin issues but needs more research for long-term safety.

New biofabrication technologies could lead to treatments for hair loss.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.

Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.

WNT signaling is crucial for skin development and healing.

Fat stem cell particles help regrow hair.

New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.

BRG1 is essential for skin cells to move and heal wounds properly.

DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.