Antifibrogenic Activities of Novel Vitamin D3 Analogs Are Dependent on VDR Expression in Human Fibroblasts

    Zorica Janjetovic, Robert C. Tuckey, Arnold E. Postlethwaite, Andrzej Słomiński
    Studysummary This study found that CYP11A1-derived vitamin D3 analogs inhibit fibroblast proliferation and decrease collagen production through VDR expression, showing potential antifibrotic and antiproliferative activity in human dermal fibroblasts.
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