Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that finasteride was associated with more reproductive adverse effects, including sexual dysfunction in men and fetal harm in women, compared to minoxidil in reported alopecia cases.

In this study, minoxidil treatment in aged mice increased elastin expression and improved aortic structure and function, suggesting its potential for arterial remodeling in aging.

In this animal study, ultrasound combined with a new microbubble formulation of minoxidil increased hair growth rates and improved follicle characteristics more effectively than minoxidil alone.

This study found that DHT treatment led to reduced cell growth, increased cell death, cell cycle arrest, ROS production, and senescence in normal human dermal papilla cells, potentially mediated by altered miRNA expression.

This study identified and updated the annotation of 61 keratin genes in dogs and horses, improving the genome annotation in these species through RNA-seq data comparison.

This study suggests that miRNAs, particularly miR-195-5p, may regulate the loss of hair follicle inductivity in cultured dermal papilla cells by suppressing the Wnt/β-catenin pathway.

This study found that extracellular vesicles from low-passage dermal papilla cells may activate hair growth by delivering miR-140-5p, which downregulates BMP2 signaling, suggesting potential therapeutic targets for alopecia.

This study found that UVB radiation significantly alters miRNA expression and induces cytotoxicity and apoptosis in normal human dermal papilla cells.

This review summarizes that polyesters hold promise for vascular tissue engineering due to their mechanical properties and biodegradability, but optimizing their use in repairing damaged blood vessels remains challenging due to the complexity of vascular tissues.

This review highlights the traditional use and potential therapeutic activities of Asiasari Radix in drug discovery, but it reports no new clinical results.

This study identified a set of tumour-suppressive microRNAs (miRNAs), termed 'normomiRs', that are highly expressed in normal tissues but low in tumors, with miR-206 and miR-381 showing significant in vitro cancer inhibition, highlighting their potential for miRNA-replacement therapies across multiple cancer types.

This study suggests that epigallocatechin gallate (EGCG) from green tea may counteract DHT-induced hair follicle damage by modifying the miRNA expression profile in human dermal papilla cells.

In this study, the researchers identified CEP135 as a biomarker linked to poor sarcoma survival and suggested PLK1 as a potential therapeutic target for sarcoma patients with high CEP135 expression.

In this study, loading niosomes with Oryza sativa bran extract altered their physical properties, suggesting potential for developing formulations aimed at anti-hair loss products.

This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.

In this study using data from young women in West Bengal, India, the researchers identified that leptin signaling impairment, insulin resistance, and specific gene mutations significantly contribute to PCOS, with obesity commonly manifesting in affected individuals.

This review compiles data on how the apelinergic system may protect against heart damage caused by doxorubicin cancer treatment, suggesting its potential to mitigate cardiotoxicity, though further research in chronic models is needed to confirm these effects and mechanisms.

This study found that knockdown of PCAT1 inhibited hair follicle regeneration in nude mice by disrupting the miR-329/Wnt10b axis and Wnt/β-catenin signaling, highlighting PCAT1's role in promoting follicle regrowth.

In this study, miR-324-3p was found to promote differentiation and migration in cultured keratinocytes and is highlighted as a potential target for treating androgenic alopecia.

This study demonstrated that troxerutin may protect human dermal papilla cells from H2O2-induced damage and suggests potential in treating alopecia by inhibiting ROS-mediated cellular damage.

In this study, transcriptome analysis identified 68 differentially expressed miRNAs in human dermal papilla cells treated with hydrogen peroxide, suggesting they play a significant role in growth arrest and apoptosis.

In this study, knockdown of XIST in 3D-cultured dermal papilla cells inhibited hair follicle regeneration by interfering with miR-424 and hedgehog signaling, highlighting XIST's role in hair development.

This study found that repeated immunization against melatonin in Australian feral goats temporarily increased cashmere production and altered growth cycles, but these effects diminished after the first year.

This study found that combining TIMP-1 with graphene oxide promoted skin tissue regeneration in rats and provided sustained release of TIMP-1 over 40 days.

This article reviews the development and use of induced pluripotent stem cell models and artificial organoids for studying neurodevelopmental disorders, but it reports no new clinical findings.

In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.

This study found that the retinoid receptor and PPAR pathway are involved in hair follicle miniaturization in androgenetic alopecia, alongside androgen receptors.

This study found that miR-221 levels in hair shafts were significantly higher in malignant melanoma patients compared to controls, suggesting potential as a non-invasive screening marker.

This study suggests that porphyra-334 may have antiaging properties, promoting collagen synthesis, improving periorbital wrinkles, and supporting hair follicle growth through gene regulation.

This study reported that the calculated and experimental electronic and vibrational properties of minoxidil were in good agreement, providing detailed insights into its molecular structure and thermal behaviors.