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Alfacalcidiol and metformin together lowered testosterone in women with PCOS, but did not significantly improve acne, hair growth, or pregnancy rates.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Young women with PCOS without additional risk factors may have normal heart function.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.

Insulin resistance is found in 20% of Thai women with PCOS, with age, waist size, skin changes, and abnormal blood fats increasing the risk.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.

Chinese women with PCOS have higher androgen levels, which change with age and weight.

Women with PCOS may have a higher risk of respiratory and ear infections due to slower nasal mucociliary clearance.

AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.

Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.

The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.

Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.

The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.

Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.

The type of PCOS a woman has doesn't strongly predict her skin or metabolic symptoms; obesity is a more important factor.

Women with different PCOS types have similar fertility treatment results.

Taking a probiotic supplement twice a day improved hair growth, skin hydration, and metabolic health in adults at risk of metabolic syndrome.

Women with nonclassical congenital adrenal hyperplasia may have a higher risk of fertility issues and miscarriages, and should get genetic counseling.

Selenium supplements can help improve symptoms and metabolic markers in lupus patients.

PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

PCOS has many symptoms, with high androgen levels being the most common.

Different treatments for PCOS should be tailored to the individual, including lifestyle changes and various medications.

Patients with acne vulgaris have lower serum irisin levels.

Hormonal imbalances, not insulin resistance or dyslipidemia, may be more important in causing acne in women over 25.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.