Management of Polycystic Ovarian Syndrome: Looking Beyond the Ovaries

April 2024 in “ Canadian Women s Health Today ”

Maria Isidora Margarita Yap‐Garcia

PCOS insulin resistance Rotterdam criteria hormonal contraceptives anti-androgens insulin sensitizers metformin pioglitazone letrozole inositols Myo-inositol D-chiro-inositol hirsutism ovulation induction Polycystic Ovarian Syndrome birth control pills anti-androgen medications insulin-sensitizing drugs Clomid

TLDR PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.

Polycystic Ovarian Syndrome (PCOS) is a complex metabolic and reproductive disorder, not just an ovarian issue. Insulin resistance, exacerbated by poor lifestyle choices, plays a key role in its pathogenesis. Diagnosis often uses the Rotterdam criteria, and management includes lifestyle interventions, hormonal contraceptives, anti-androgens, and insulin sensitizers like metformin and pioglitazone. Screening for cardiovascular disease, endometrial pathology, sleep apnea, and mental health disorders is crucial. For pregnancy, letrozole is preferred for ovulation induction. Inositols, especially Myo-inositol and D-chiro-inositol, show promise in improving ovulation, reducing hirsutism, aiding weight loss, and enhancing embryo quality in IVF. Treatment focuses on lifestyle changes and tailored pharmacologic therapies to address various symptoms and complications.

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Research cited in this study

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Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome

research Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome

2 citations, August 2023 in “Human Reproduction”

The document provides updated advice on how to diagnose and treat polycystic ovary syndrome.

research Serum Anti-Müllerian Hormone as a Predictor of Polycystic Ovarian Syndrome Among Women of Reproductive Age

4 citations, May 2022 in “BMC Women's Health”

High levels of anti-Müllerian hormone can indicate polycystic ovarian syndrome in women who can have babies.

research Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee

49 citations, February 2019 in “The Journal of Clinical Endocrinology and Metabolism”

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Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

research Diagnosis and Treatment of Polycystic Ovary Syndrome: A Comparative Review

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PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.

research Polycystic Ovary Syndrome: Diagnosis and Treatment

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PCOS is a common hormonal disorder in women, treated with lifestyle changes and medications like hormonal contraceptives and metformin.

research Polycystic Ovary Syndrome: Update on Diagnosis and Treatment

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The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

research Polycystic Ovary Syndrome: Management of a Long-Term Condition in Primary Care

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Manage PCOS in primary care with weight loss, psychological support, medication, and monitoring for health risks.

Management of Polycystic Ovarian Syndrome: Looking Beyond the Ovaries

Research cited in this study

research Recommendations From The 2023 International Evidence-Based Guideline For The Assessment And Management Of Polycystic Ovary Syndrome

research Serum Anti-Müllerian Hormone as a Predictor of Polycystic Ovarian Syndrome Among Women of Reproductive Age

research Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee

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