TLDR High levels of anti-Müllerian hormone can indicate polycystic ovarian syndrome in women who can have babies.
The study involved 98 women, 51 of whom were newly diagnosed with polycystic ovarian syndrome (PCOS). The research found that elevated serum anti-Müllerian hormone (AMH) levels can be a strong predictor for diagnosing PCOS in women of reproductive age. Women with high AMH levels (≥ 3.9 ng/ml) showed a significant difference in ovarian morphology compared to the normal AMH group. The study also found a significant relationship between high AMH levels and luteinizing hormone (LH), and that AMH levels tend to increase with weight, menstrual abnormalities, and hirsutism. The study concluded that AMH could be used as a diagnostic tool for PCOS, with a cut-off value of 3.9 ng/mL.
1265 citations,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
1540 citations,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
4809 citations,
January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
249 citations,
November 2003 in “Clinical endocrinology” Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
30 citations,
January 2019 in “Clinical Endocrinology” The study concluded that both anti-Mullerian hormone and LH/FSH ratio are higher in women with PCOS and combining these markers with BMI could improve diagnosis accuracy.
16 citations,
September 2018 in “Clinical Biochemistry” The document concludes that more research is needed to fully understand the causes of PCOS.
February 2022 in “Research Square (Research Square)” High levels of Anti-Müllerian Hormone (AMH) in the blood can strongly predict Polycystic Ovarian Syndrome (PCOS) and related issues in women of reproductive age.
883 citations,
August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
12 citations,
January 2016 in “Journal of Assisted Reproduction and Genetics” Certain gene variations are linked to higher male hormone levels in Chinese women with PCOS and insulin resistance.