Serum Anti-Müllerian Hormone as a Predictor of Polycystic Ovarian Syndrome Among Women of Reproductive Age

    May 2022 in “ BMC Women's Health ”
    Muhammad Salman Butt, Javeria Saleem, Sobia Aiman, Rubeena Zakar, Iftikhar Sadique, Florian Fischer
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    TLDR High levels of anti-Müllerian hormone can indicate polycystic ovarian syndrome in women who can have babies.
    The study involved 98 women, 51 of whom were newly diagnosed with polycystic ovarian syndrome (PCOS). The research found that elevated serum anti-Müllerian hormone (AMH) levels can be a strong predictor for diagnosing PCOS in women of reproductive age. Women with high AMH levels (≥ 3.9 ng/ml) showed a significant difference in ovarian morphology compared to the normal AMH group. The study also found a significant relationship between high AMH levels and luteinizing hormone (LH), and that AMH levels tend to increase with weight, menstrual abnormalities, and hirsutism. The study concluded that AMH could be used as a diagnostic tool for PCOS, with a cut-off value of 3.9 ng/mL.
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