Diagnosis and Treatment of Polycystic Ovary Syndrome: A Comparative Review

    March 2022 in “ International journal of pharmaceutical sciences review and research ”
    Hindola Kancherla, Gayathri Konduri, Ramya Balaprabha, Rama V. N. Rao
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    TLDR PCOS is a hormonal issue in women that is usually treated with birth control pills, metformin, and lifestyle changes, with early treatment helping to reduce complications and improve life quality.
    Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women of reproductive age, with four possible phenotypes. The main goal of treatment is symptom management, with oral contraceptives being the first line of therapy. Metformin is also used, particularly in overweight women, to improve insulin sensitivity and decrease androgen levels, but it's less effective in markedly obese women. Other treatments include clomiphene citrate, cyproterone acetate, Flutamide, spironolactone, Finasteride, and ketoconazole. For hyperandrogenism symptoms like hirsutism and acne, supportive treatments and lifestyle modifications are recommended. A study of 200 participants found no difference in quality of life between different types of oral contraceptives after 3 months, but after 6 months, those treated with Cyproterone acetate had an increased quality of life score. The document emphasizes the importance of early intervention to minimize complications and promote a healthier lifestyle.
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      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  55 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community C’est terrible - at my wits end

      in Female  443 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

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