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    Did you mean HLA-DR?
    Glossary HLA-DR

    protein on immune cells presenting antigens to trigger responses

    HLA-DR is a part of the human immune system, specifically a protein found on the surface of certain cells that helps the body distinguish between its own cells and foreign invaders. It plays a crucial role in the immune response by presenting pieces of proteins (antigens) to immune cells, which can then trigger an immune reaction. This protein is also involved in autoimmune conditions, where the immune system mistakenly attacks the body's own tissues.

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    1. Exomic Sequencing of Immune-Related Genes Reveals Novel Candidate Variants Associated with Alopecia Universalis PLoS ONE · 2013 · 18 citations
    2. Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles Clinical, cosmetic and investigational dermatology · 2023 · 1 citations
    3. The genetic basis of dermatophytosis skin infection susceptibility Nature Communications · 2026
    4. Cell Surface B2m-Free Human Leukocyte Antigen (HLA) Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA? Biomolecules · 2023 · 3 citations
    5. Wasabi leaf extract changes the expression levels of cytokine related genes in dermal papilla cells, which identified by the whole transcriptome 2025
    6. Functional Interpretation of Genome-Wide Association Study Evidence in Alopecia Areata Journal of Investigative Dermatology · 2015 · 55 citations
    7. Investigating the Genetic Association of Selected Candidate Loci with Alopecia Areata Susceptibility in Jordanian Patients Medicina · 2025 · 1 citations
    8. Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa Frontiers in medicine · 2021 · 22 citations
    9. Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 Nature Communications · 2019 · 115 citations
    10. Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein Scientific Reports · 2018 · 27 citations
    11. Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status European journal of endocrinology · 1999 · 19 citations
    12. Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 MKG2D Lymphocytes of Alopecia Areata Patients 2018 · 15 citations
    13. Frontal fibrosing alopecia and lichen planopilaris in HLA-identical mother and daughter Indian Journal of Dermatology, Venereology and Leprology · 2015 · 12 citations
    14. Human Adipose-Derived Mesenchymal Stromal Cells Exhibit High HLA-DR Levels and Altered Cellular Characteristics under a Xeno-free and Serum-free Condition Stem Cell Reviews and Reports · 2021 · 12 citations
    15. Study of Human Leukocyte Antigen ( HLA ) in 13 cases of familial frontal fibrosing alopecia: CYP 21A2 gene p.V281L mutation from congenital adrenal hyperplasia linked to HLA class I haplotype HLA ‐ A*33:01 ; B*14:02; C*08:02 as a genetic marker Australasian Journal of Dermatology · 2019 · 7 citations
    16. Joint study of the associations of HLA‐B and the transmembrane short tandem repeat polymorphism of MICA protein with alopecia areata shows independent associations of both with the disease Clinical and Experimental Dermatology · 2020 · 7 citations
    17. HLA-B27 Antigen in Women With Ankylosing Spondylitis JAMA · 1976 · 7 citations
    18. Changes in Populations of HLA- DR+CD3+ Cells and CD57–CD16+ Cells in Alopecia areata after Corticosteroid Therapy Dermatology · 1994 · 5 citations
    19. Alopecia areata after HLA-identical BMT from an affected, sibling donor Bone marrow transplantation · 2014 · 4 citations
    20. [Significance of HLA-DR+ T cells and natural killer (NK) cells in the peripheral blood lymphocytes of alopecia areata (AA)]. PubMed · 1990 · 2 citations
    21. HLA‐B alleles associated with frontal fibrosing alopecia in Brazil may share similar peptide presentation and T‐cell interaction profiles Journal of the European Academy of Dermatology and Venereology · 2024 · 1 citations
    22. Genotyping of the rs1800440 Polymorphism in CYP1B1 Gene and the rs9258883 Polymorphism in HLA-B Gene in a Spanish Cohort of 223 Patients with Frontal Fibrosing Alopecia Acta dermato-venereologica · 2023 · 1 citations
    23. Alopecia Areata is associated with MICA and an extended HLA haplotype Journal of the American Academy of Dermatology · 2004 · 1 citations
    24. Immunogenetic and metabolic risk factors in male androgenetic alopecia: the role of HLA-DRB1 alleles and vitamin D3 deficiency 2025
    25. Human Adipose-derived Mesenchymal Stromal Cells Exhibit High HLA-DR Levels and Altered Cellular Characteristics under a Xeno-free and Serum-free Condition Research Square (Research Square) · 2021
    26. Linking allergy to mercury to HLA and burning mouth syndrome Journal of the European Academy of Dermatology and Venereology · 2007 · 6 citations
    27. Genome-wide association study in alopecia areata implicates both innate and adaptive immunity Nature · 2010 · 717 citations
    28. Alopecia areata update Journal of The American Academy of Dermatology · 2010 · 391 citations
    29. Familial aggregation of alopecia areata Journal of the American Academy of Dermatology · 2016 · 295 citations
    30. Lymphocytes, neuropeptides, and genes involved in alopecia areata Journal of Clinical Investigation · 2007 · 286 citations