Exomic Sequencing of Immune-Related Genes Reveals Novel Candidate Variants Associated with Alopecia Universalis

January 2013 in “ PLoS ONE ”

Seungbok Lee, Seung Hwan Paik, Hyun Jin Kim, Hyeong Ho Ryu, Soeun Cha, Seong Jin Jo, Hee Chul Eun, Jeong‐Sun Seo, Jong‐Il Kim, Oh Sang Kwon

alopecia universalis alopecia areata HLA-DRB5 BTNL2 HLA-DMB TLR1 PMS2 HLA-A single nucleotide polymorphisms AU AA SNPs

Studysummary This study identified several significant genetic variants associated with alopecia universalis, including a novel association with HLA-DRB5, which may play a hidden role in the disease.

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