Linear Immunoglobulin A/Immunoglobulin G Bullous Dermatosis Associated with Vogt-Koyanagi-Harada Disease

    May 2011 in “ The Journal of Dermatology ”
    Shigeto Yanagihara, Hiromi Kobayashi, Akiko Naruse, Chiharu Tateishi, Daisuke Tsuruta, Masamitsu Ishii
    TLDR A man had two rare autoimmune diseases that might be connected.
    The document reported a case of a 35-year-old Japanese male with combined linear immunoglobulin A/immunoglobulin G bullous dermatosis (LAGBD) and Vogt-Koyanagi-Harada disease. The patient exhibited human leukocyte antigen typing of −A24, B52, C*1202, DR*1502, DQ*0601, and immunoblot analysis showed reactivity to both 180- and 230-kDa proteins at the IgA and IgG levels. The authors suggested a possible association between Vogt-Koyanagi-Harada disease and LAGBD due to their common link with autoimmune diseases, although they could not rule out the possibility of coincidence.
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