17 citations
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April 2021 in “Frontiers in Pharmacology”
This review discusses the role of Nrf2 in hearingloss and its potential as a target for developing hearing protection drugs, but reports no new clinical results.
This study found that administering calcium blockers verapamil or nimodipine significantly preserved auditory function and hair cell survival in Cx26-cKO mice, suggesting potential protective effects for other inner ear disorders.
This study found that targeting CISD1 with the compound NL-1 reduced mitochondrial dysfunction and reactive oxygen species accumulation, protecting against cisplatin-induced hearingloss in cell models and mice, without affecting cisplatin's cancer-fighting effectiveness.
December 2021 in “OPAL (Open@LaTrobe) (La Trobe University)”
This study found that knocking out the Hars2 gene in mouse cochlear hair cells led to mitochondrial dysfunction and ROS stress, resulting in progressive hearingloss and differential effects on inner and outer hair cells.
The conversation is about enhancing dermarolling for hair loss by using topical peptides like tb-500 or GHK-Cu to aid in healing and hair growth, and whether anyone has experienced significant results from this method.
The user experienced hair loss after switching to daily microneedling and stopping tretinoin, while continuing oral finasteride, minoxidil, and other treatments. The consensus suggests daily microneedling is excessive and harmful, recommending less frequent sessions to allow healing.
The conversation discusses an experiment involving hair loss treatments, including the use of Verteporfin, KY19382, dutasteride, oral and topical minoxidil, AHK-Cu, and microneedling. The experiment aims to test the effectiveness of these treatments in promoting hair growth and healing without scarring, with updates planned every few months.
A 20-year-old is planning a hair transplant in Thailand before joining the military and is concerned about healing time. They have used finasteride, minoxidil, and dutasteride for hair loss and are advised to be cautious with grafts and expect healing within a month or two.
A 33-year-old male is seeking advice on reversing grey hair while using minoxidil, finasteride, ketoconazole, derma rolling, cold baths, and leg exercises for hair loss. Another user mentions hearing about GHK-Cu for grey hair reversal.
Is a hair transplant painful?Clinics say local anaesthetic makes the procedure itself mostly comfortable, but the anaesthetic injections sting and soreness for a few days afterwards is common. Pain varies from person to person.
Do hair transplants look natural?Clinics say a well-done transplant can look natural, but results vary with the surgeon, your hair and donor supply, and scars can show with very short hair.
What microneedling is?Microneedling uses fine needles to make tiny skin wounds that trigger healing. Some devices are FDA-authorized for acne scars; none is authorized for hair loss, where evidence comes mainly from small studies.