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    GlossaryStem Cell Loss

    reduction of regenerative cells impairing tissue repair and growth

    Stem cell loss refers to the reduction or depletion of stem cells in a particular tissue or organ. Stem cells are crucial for regenerating and repairing tissues, so their loss can lead to impaired healing and tissue degeneration. In the context of hair, stem cell loss in hair follicles can contribute to conditions like alopecia, where hair growth is significantly reduced or halted.

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      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

      learn Microneedling

      technique to create small wounds in skin to activate collagen production and hair growth

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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community STEM CELL TREATMENT FOR HAIR LOSS at home

      in Treatment  6 upvotes 3 years ago
      User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.

      community Seeking Advice: Stem Cell Therapy vs. PRP for Hair Loss

      in Treatment  2 upvotes 5 months ago
      The conversation is about someone seeking advice on choosing between stem cell therapy and PRP for treating hair loss, asking for personal results, side effects, overall satisfaction, and recommendations from others.

      community PP405 - hair stem cell stimulation

      in Research/Science  51 upvotes 6 months ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.