33 citations
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September 2019 in “Dermatologic Surgery” This study found that intradermal administration of adipose-derived stem cell–conditioned medium significantly increased hair density and dermal thickness, suggesting potential regenerative effects on both hair follicles and the interfollicular scalp in patients with alopecia.
45 citations
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January 2021 in “Stem Cell Research & Therapy” This study found that incorporating adipose-derived stem cell conditioned medium into a polysaccharide hydrogel effectively reduced scar hyperplasia, with the combination offering better outcomes in preventing hypertrophic scarring compared to the medium alone in a rabbit ear model.
23 citations
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June 2015 in “Oncology Letters” This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.
January 2010 in “Seoul National University Open Repository (Seoul National University)” This review discusses the growth factors produced by adipose tissue-derived stem cells that are associated with hair growth stimulation and reports no new clinical findings.
March 2025 in “Regenerative Therapy” This study suggests that SACM may enhance hair growth more effectively than non-treated ACM, highlighting the potential of S. maxima as a promising agent for use in pharmaceutical and cosmeceutical industries.