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GlossaryVascularized Adipose Tissue

fat tissue rich in blood vessels

Vascularized Adipose Tissue (VAT) refers to fat tissue that is rich in blood vessels. This type of tissue is important because the blood vessels supply the necessary nutrients and oxygen, which can enhance the survival and function of the fat cells. In medical and cosmetic procedures, such as fat grafting, ensuring that the adipose tissue is well-vascularized can improve the success and longevity of the treatment.

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Efficacy and Safety of Autologous Adipose-Derived Stromal Vascular Fraction Enriched with Platelet-Rich Plasma in Flap Repair of Transsphincteric Cryptoglandular Fistulas

research Efficacy and Safety of Autologous Adipose-Derived Stromal Vascular Fraction Enriched with Platelet-Rich Plasma in Flap Repair of Transsphincteric Cryptoglandular Fistulas

16 citations , October 2021 in “Techniques in Coloproctology”

Using SVF enriched with PRP in surgery for certain fistulas is effective and safe.

research 4D Polycarbonates via Stereolithography as Scaffolds for Soft Tissue Repair

101 citations , July 2021 in “Nature Communications”

4D polycarbonate scaffolds show promise for soft tissue repair due to their biocompatibility, shape memory, and minimal immune response.

research Bioengineering Skin Constructs

1 citations , November 2014 in “Elsevier eBooks”

Future research should focus on making bioengineered skin that completely restores all skin functions.

research Design of a Multifunctional Biomaterial Inspired by Ancient Chinese Medicine for Hair Regeneration in Burned Skin

45 citations , March 2020 in “ACS Applied Materials & Interfaces”

The new biomaterial inspired by ancient Chinese medicine effectively promotes hair growth and heals wounds in burned skin.

research Biomimetic Scaffolds: A Novel Approach to Three-Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering

1 citations , March 2024 in “Nanomaterials”

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

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community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 2 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Proposed new pathogenesis model for androgenetic alopecia (AGA)

in Research/Science 7 upvotes 2 years ago

The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Topical Dutasteride - Dosage / Frequency (Strut gel formulation)

in Treatment 15 upvotes 4 years ago

A user ordered a topical dutasteride gel with tretinoin for hair loss after unsatisfactory results with minoxidil and finasteride. Another user shared their experience with the same product, noting its pleasant smell and feel but difficulty in application and uncertainty about its absorption and frequency of use.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 1 year ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

in Research/Science 63 upvotes 1 year ago

The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

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