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The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Collagen XVII is important for skin aging and wound healing.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Hair follicle stem cells help skin heal and grow during stretching.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.

LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.

A fragment of human type XVII collagen shows great potential for skin health and wound healing.

Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.

New technologies show promise for better hair regeneration and treatments.

Stress hormone corticosterone suppresses hair growth by affecting stem cell activity and Gas6 protein expression.

Type 1 Diabetes prevents hair growth by causing cell death in hair follicles.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

A new microneedle patch made from hair proteins helps regrow hair faster and better than current treatments.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Immune cells affect hair growth and could lead to new hair loss treatments.

A substance called Vascular Endothelial Growth Factor can protect certain hair follicle stem cells from damage caused by androgens, suggesting a new possible treatment for hair loss.

Lymphatic vessels are important for skin repair and could affect skin disease treatments.

Dog hair follicle stem cells can turn into fat cells.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.