7 citations,
April 2020 in “Dermatologic Therapy” Dexpanthenol improves hair growth in male baldness.
268 citations,
April 2009 in “International Journal of Pharmaceutics” Niosomes improve minoxidil skin delivery for hair loss treatment.
128 citations,
July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.
122 citations,
April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
93 citations,
January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
74 citations,
June 2010 in “European Journal of Pharmaceutics and Biopharmaceutics” Minoxidil foam enters hair follicles and skin for hair growth.
39 citations,
April 2010 in “International Journal of Pharmaceutics” Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.
31 citations,
March 2013 in “Gene” Signaling pathways are crucial for hair growth in goats.
30 citations,
December 2017 in “Medical Hypotheses” The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.
25 citations,
September 2014 in “Biological Research” Arctiin helps protect hair cells from damage and death caused by oxidative stress.
22 citations,
May 2000 in “American Journal of Clinical Dermatology” Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.
12 citations,
July 2020 in “International Journal of Pharmaceutics” Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.
6 citations,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
3 citations,
November 2014 in “Protein Expression and Purification” Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.
211 citations,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
156 citations,
October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
76 citations,
January 2007 in “American Journal of Clinical Dermatology” Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
72 citations,
January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
60 citations,
June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
57 citations,
September 2017 in “Journal of controlled release” Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.
52 citations,
November 2013 in “European Journal of Pharmaceutical Sciences” Chitosan-decorated polymersomes improve finasteride delivery for hair loss treatment.
44 citations,
April 2012 in “American Journal of Clinical Dermatology” Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
33 citations,
June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
30 citations,
September 2017 in “Clinics in Dermatology” Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
23 citations,
February 2020 in “PLOS genetics” Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
22 citations,
January 2015 in “The Cochrane library” DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
11 citations,
March 2009 in “Bioorganic & Medicinal Chemistry Letters” Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.
8 citations,
November 2020 in “Optics and Laser Technology” LED light therapy is effective for skin and hair treatments but requires careful use to minimize risks.
6 citations,
August 2020 in “Journal of Pharmaceutical Innovation” Nanoemulgel improves hair growth and quality using finasteride without irritation.
4 citations,
July 2013 in “Journal of Dermatological Science” Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.