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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Long scalp hair evolved for cooling and social signaling.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

Older mice have stiffer skin with less elasticity due to changes in collagen and skin structure, affecting aging and hair loss.

Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.

Different types of cells in the eye express specific keratins at various stages of development.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Myc activation reduces skin stem cells by affecting cell adhesion.

The document concludes that accurate diagnosis of hair loss in children is crucial due to limited treatment options and the condition's psychological impact.

Oral minoxidil shows promise in treating monilethrix-related hair loss.

The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

K16 can partially replace K14 but causes hair loss and skin issues.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.

Targeting CXCL12 may help treat hair loss caused by androgens.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Notch signaling disruptions can cause various skin diseases.

The 1891 epidemic skin disease was likely caused by arsenic poisoning, possibly from beer or fish.