Protective Mechanism of Adipose-Derived Stem Cells in Remodeling of the Skin Stem Cell Niche During Photoaging

    January 2018 in “ Cellular Physiology and Biochemistry ”
    Meihua Gong, Pan Zhang, Chunyang Li … Daping Yang
    Studysummary This study found that UVB irradiation alters skin stem cell niches leading to signs of photoaging, which may be reversed by adipose-derived stem cells through BMP4 pathway modulation and niche remodeling.
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    Research cited in this study 9

    1. Neural Stem Cells Restore Hair Growth Through Activation of the Hair Follicle Niche Cell Transplantation · 2016
    2. Gab1 and MAPK Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence Cell reports · 2015
    3. The Modulatable Stem Cell Niche: Tissue Interactions During Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015
    4. Regenerative Hair Waves in Aging Mice and Extra-Follicular Modulators Follistatin, Dkk1, and Sfrp4 Journal of Investigative Dermatology · 2014
    5. Estrogen Leads to Reversible Hair Cycle Retardation Through Inducing Premature Catagen and Maintaining Telogen PLOS ONE · 2012
    6. Dynamic Signals for Hair Follicle Development and Regeneration Stem Cells and Development · 2011
    7. Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells Science · 2011
    8. Scratching the Surface of Skin Development Nature · 2007
    9. BMP Signaling in the Control of Skin Development and Hair Follicle Growth Differentiation · 2004

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    1. Protective Mechanism of Adipose-Derived Stem Cells in Remodeling of the Skin Stem Cell Niche During Photoaging Cellular Physiology and Biochemistry · 2018