18 citations
,
June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” A gene called Gk5 controls lipid production in the skin and affects hair growth.
40 citations
,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
July 2023 in “Cosmetics” New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
9 citations
,
April 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.
9 citations
,
April 2021 in “Frontiers in Immunology” Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
November 2022 in “Gigascience” A specific genetic deletion in goats affects cashmere yield and thickness.
1 citations
,
March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
May 2022 in “Cardiovascular Toxicology” 9 citations
,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
14 citations
,
July 2016 in “Anatomical Science International” The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.
11 citations
,
July 2020 in “Life sciences” Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.
134 citations
,
August 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
55 citations
,
June 2018 in “Journal of Cosmetic Dermatology” Platelet-rich plasma, taken from a person's own blood, can help rejuvenate skin, stimulate hair growth, and treat hair loss, but more research is needed to confirm its safety and effectiveness.
8 citations
,
January 2017 in “Stem Cells International” A protein called sFRP4 from skin cells stops the development of pigment-producing cells in hair.
4 citations
,
November 2023 in “Frontiers in immunology” New treatments targeting T-cell pathways are needed for better alopecia areata management.
10 citations
,
September 2018 in “Experimental Dermatology” Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.
3 citations
,
February 2013 in “Annals of Diagnostic Pathology” AIDS may cause changes in the scalp that increase infection risk and hair loss.
68 citations
,
January 2012 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
126 citations
,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
37 citations
,
January 2016 in “Drug design, development and therapy” Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.
27 citations
,
July 2017 in “European Journal of Dermatology” Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
April 2024 in “International journal of molecular sciences” Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
11 citations
,
December 2018 in “Bone” Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
4 citations
,
November 2022 in “Frontiers in Immunology” Lung and liver macrophages protect our tissues and their dysfunction can cause various diseases.
60 citations
,
May 2015 in “Biomaterials” A surface with VEGF can specifically capture endothelial cells from flowing fluids.
70 citations
,
March 2021 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.
1 citations
,
June 2023 in “Advances in therapy” Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.
49 citations
,
January 2022 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
3 citations
,
April 2015 in “American journal of biomedical sciences” Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.
22 citations
,
July 2012 in “Journal of integrative agriculture/Journal of Integrative Agriculture” Hoxc13 is linked to seasonal hair growth in Cashmere goats and is affected by melatonin.