72 citations,
November 2012 in “PloS one” The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
3 citations,
January 2024 in “Signal transduction and targeted therapy” Lymphatic vessels are essential for health and can be targeted to treat various diseases.
22 citations,
August 2020 in “Cells” TGM3 is important for skin and hair structure and may help diagnose cancer.
5 citations,
January 2021 in “Frontiers in Cell and Developmental Biology” Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.
December 2023 in “Animals” The study mapped yak skin cells to understand hair growth better.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
39 citations,
September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
13 citations,
June 2014 in “Molecular therapy” The lentiviral array can monitor and predict gene activity during stem cell differentiation.
16 citations,
March 2021 in “EvoDevo” Different species use the same genes for tooth regeneration.
266 citations,
January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
September 2023 in “Animals” Genes linked to wool fineness in sheep have been identified.
April 2016 in “Journal of Investigative Dermatology” Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
July 2024 in “ADMET & DMPK” Surface-modified nanostructured lipid carriers can improve hair growth treatments.
23 citations,
January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
14 citations,
April 2019 in “Genes” Researchers found a genetic region that influences the number of coat layers in dogs.
12 citations,
June 2021 in “Scientific Reports” Curcumin may help reverse aging by targeting specific genes.
12 citations,
November 2014 in “PLOS Computational Biology” The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
7 citations,
November 2022 in “Communications biology” Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
5 citations,
October 2014 in “Methods” The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
132 citations,
August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
24 citations,
May 2019 in “PLOS genetics” Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
13 citations,
June 2020 in “Stem Cells International” A substance from a specific gel helped to grow hair effectively in mice, suggesting it could potentially be used to treat hair loss in humans.
4 citations,
November 2020 in “BMC Dermatology” Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.
6 citations,
March 2021 in “Journal of Cosmetic Dermatology” PRP injections promote hair growth and increase hair density in androgenic alopecia.
2 citations,
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.
December 2014 in “Bali Medical Journal” Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.
103 citations,
June 2018 in “International Journal of Molecular Sciences” FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.
10 citations,
October 2016 in “Experimental Dermatology” Nail stem cells and Wnt signaling are important for fingertip regeneration but not sufficient for regenerating more complex limb structures.
119 citations,
November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.