2 citations,
January 2022 in “Journal of Investigative Dermatology” Hedgehog signaling in skin cells is crucial for hair growth and skin healing, but needs to be balanced to avoid harmful effects like scarring and cancer.
47 citations,
June 2019 in “Nature Communications” Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
8 citations,
May 2018 in “The Journal of Allergy and Clinical Immunology” Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
25 citations,
June 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” VDR regulation varies by tissue and is crucial for its biological functions.
54 citations,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin A affects hair loss and immune response in alopecia areata.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating TLR9 helps heal large wounds and regrow hair by involving a specific type of immune cell.
1 citations,
November 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Glutamic acid helps mice grow hair.
3 citations,
May 2022 in “Oncogene” Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.
April 2023 in “Journal of Investigative Dermatology” cp-asiAR may effectively treat hair loss by targeting androgen receptors.
13 citations,
September 2012 in “Cell & tissue research/Cell and tissue research” pCLCA2 protein may help maintain skin structure and function.
1 citations,
April 2018 in “Journal of Investigative Dermatology” Fzd2 is important for skin and hair development through various signaling ways.
April 2018 in “Journal of Investigative Dermatology” Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
126 citations,
October 1998 in “Experimental Dermatology” The hr gene is crucial for skin and hair health, with mutations causing hair disorders.
23 citations,
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” NF-κB is crucial for different stages and types of hair growth in mice.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
6 citations,
August 2015 in “Acta histochemica” Lysozyme might help mouse hair grow.
June 2011 in “Expert Review of Dermatology” Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.
16 citations,
May 2011 in “The Journal of clinical investigation/The journal of clinical investigation” Some skin tumors may start from hair follicle stem cells.
57 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
7 citations,
October 2015 in “Experimental dermatology” Blocking the mineralocorticoid receptor can help treat skin thinning caused by steroids.
245 citations,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
9 citations,
August 2022 in “Frontiers in Pharmacology” Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.
328 citations,
November 2020 in “Nature Materials” Hydrogel scaffolds can help wounds heal better and grow hair.
1 citations,
January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dicer is crucial for hair growth in mice.
45 citations,
August 2018 in “Haematologica” Macrophage iron release is crucial for hair growth and wound healing.
November 2023 in “Frontiers in veterinary science” The study provides insights into hair growth mechanisms in yaks.
1 citations,
January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Hair follicles could be used to deliver drugs effectively, with the right understanding and methods.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.