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Stem cell niches support, regulate, and coordinate stem cell functions.

Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Only skin melanocytes, not other types, can color hair in mice.

Surgical repigmentation can permanently restore color to white hair in vitiligo patients.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.

The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.

Hair color is determined by melanin produced and transferred in hair follicles.

Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Skin organoids from stem cells can help study and treat skin issues but face some challenges.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Hair growth and development are controlled by specific signaling pathways.

Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.

SOX9 is essential for the development of various organs and hair follicles.

Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.

Hydrogel microcapsules help create cells that boost hair growth.

Blocking β-catenin in skin cells improves hair growth during wound healing.

Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.