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    Glossary Gsdma3

    gene involved in hair follicle development and skin health

    Gsdma3 stands for Gasdermin A3, a gene that plays a crucial role in hair follicle development and skin health. Mutations in this gene can lead to hair loss (alopecia) and skin abnormalities, making it a significant focus in dermatological and genetic research.

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    Research 30 of 56

    1. Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation American Journal Of Pathology · 2011 · 54 citations
    2. Gsdma3 is required for hair follicle differentiation in mice Biochemical and biophysical research communications · 2010 · 30 citations
    3. In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining Experimental Dermatology · 2011 · 15 citations
    4. Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway Oncotarget · 2017 · 11 citations
    5. Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice Acta histochemica · 2012 · 11 citations
    6. <i>In vivo</i> response of GsdmA3<sup>Dfl</sup>/+ mice to topically applied fish oil – effects on cellular markers and macrophages FEBS open bio · 2016 · 1 citations
    7. GSDMA deficiency impairs cutaneous squamous cell carcinoma growth Frontiers in Oncology · 2026
    8. Study on the skin structure, hair follicle cycle, and GSDMA protein expression in Ganxi goats Frontiers in Veterinary Science · 2025 · 1 citations
    9. N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting Journal of biomedical science · 2015 · 76 citations
    10. Roles of GasderminA3 in Catagen–Telogen Transition During Hair Cycling Journal of Investigative Dermatology · 2015 · 25 citations
    11. Depletion of <i>Gsdma1/2/3</i> alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway Journal of Molecular Cell Biology · 2023 · 6 citations
    12. 880 Gasdermin A3-mediated cell death causes niche collapse and precocious activation of hair follicle stem cells Journal of Investigative Dermatology · 2019 · 2 citations
    13. Inducible expression of gasdermin A3 in the epidermis causes epidermal hyperplasia and skin inflammation Experimental Dermatology · 2015 · 12 citations
    14. Modulating hair follicle size with <i>Wnt10b/DKK1</i> during hair regeneration Experimental Dermatology · 2014 · 53 citations
    15. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014 · 53 citations
    16. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    17. Stem cells and alopecia: a review of pathogenesis British Journal of Dermatology · 2012 · 33 citations
    18. Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias Experimental Dermatology · 2018 · 22 citations
    19. Context-dependent effect of sPLA2-IIA induced proliferation on murine hair follicle stem cells and human epithelial cancer EBioMedicine · 2019 · 13 citations
    20. MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysis Scientific Reports · 2025 · 12 citations
    21. Expression and localization of Sox10 during hair follicle morphogenesis and induced hair cycle International Journal of Medical Sciences · 2021 · 9 citations
    22. Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle Stem Cells International · 2017 · 8 citations
    23. Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response Scientific Reports · 2017 · 7 citations
    24. Rhamnose-mediated modulation of hair follicle growth: insights from chemical genomics bioRxiv (Cold Spring Harbor Laboratory) · 2025
    25. AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    26. Obtenção e caracterização das células-tronco do folículo piloso de fetos caninos 2016
    27. In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators Nature Cell Biology · 2014 · 173 citations
    28. Development and homeostasis of the sebaceous gland Seminars in Cell & Developmental Biology · 2012 · 107 citations
    29. Aberrant inflammasome activation as a driving force of human autoimmune skin disease Frontiers in immunology · 2023 · 3 citations
    30. Regenerative potential of CD200- subpopulations of hair follicle bulge Frontiers in Cell and Developmental Biology · 2026