Gasdermin A3-Mediated Cell Death Causes Niche Collapse and Precocious Activation of Hair Follicle Stem Cells

    April 2019 in “ Journal of Investigative Dermatology ”
    S. Li, Wei-Jeng Suen, Chyuan Haur Kao … Liang‐Tung Yang
    Studysummary This study found that overexpression of Gasdermin A3 in mice disrupts the hair follicle stem cell niche and causes hair loss through cell necrosis and abnormal hair cycle progression, without involving immune-mediated mechanisms.
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