research N-Terminal Functional Domain of Gasdermin A3 Regulates Mitochondrial Homeostasis via Mitochondrial Targeting
Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.
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5 / 81 results research Inducible Expression of Gasdermin A3 in the Epidermis Causes Epidermal Hyperplasia and Skin Inflammation
Gasdermin A3 overexpression in skin causes inflammation and hair loss.
research Depletion of Gsdma1/2/3 Alleviates PMA-Induced Epidermal Hyperplasia by Inhibiting the EGFR–Stat3/Akt Pathway
Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.
research A Missense Mutation in Lama3 Causes Androgen Alopecia
A gene mutation in Lama3 is linked to a common type of hair loss.
research Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation
A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.
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