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    Glossary Gasdermin A3

    protein crucial for hair follicle development and growth

    Gasdermin A3 is a protein that plays a crucial role in the regulation of hair follicle development and hair growth. It is part of the gasdermin family, which is involved in cell differentiation and apoptosis (programmed cell death). Mutations or dysregulation of Gasdermin A3 can lead to hair disorders, such as alopecia, where hair loss occurs due to the disruption of normal hair follicle function.

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    1. N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting Journal of biomedical science · 2015 · 76 citations
    2. Inducible expression of gasdermin A3 in the epidermis causes epidermal hyperplasia and skin inflammation Experimental Dermatology · 2015 · 12 citations
    3. 880 Gasdermin A3-mediated cell death causes niche collapse and precocious activation of hair follicle stem cells Journal of Investigative Dermatology · 2019 · 2 citations
    4. Roles of GasderminA3 in Catagen–Telogen Transition During Hair Cycling Journal of Investigative Dermatology · 2015 · 25 citations
    5. Depletion of <i>Gsdma1/2/3</i> alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway Journal of Molecular Cell Biology · 2023 · 6 citations
    6. Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study Current Issues in Molecular Biology · 2021 · 1 citations
    7. Effects of Acanthus ebracteatus Vahl. extract and verbascoside on human dermal papilla and murine macrophage Scientific Reports · 2022 · 7 citations
    8. Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition From Telogen to Anagen Phase Frontiers in Cell and Developmental Biology · 2022 · 5 citations
    9. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014 · 53 citations
    10. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
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