Search

for
Search:

GlossaryGasdermin A3

protein crucial for hair follicle development and growth

Gasdermin A3 is a protein that plays a crucial role in the regulation of hair follicle development and hair growth. It is part of the gasdermin family, which is involved in cell differentiation and apoptosis (programmed cell death). Mutations or dysregulation of Gasdermin A3 can lead to hair disorders, such as alopecia, where hair loss occurs due to the disruption of normal hair follicle function.

Related Terms

Learn

0 / 0 results

— no results

Research

5 / 69 results

research N-Terminal Functional Domain of Gasdermin A3 Regulates Mitochondrial Homeostasis via Mitochondrial Targeting

76 citations , June 2015 in “Journal of biomedical science”

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

research Gasdermin A3-Mediated Cell Death Causes Niche Collapse and Precocious Activation of Hair Follicle Stem Cells

2 citations , April 2019 in “Journal of Investigative Dermatology”

Gasdermin A3 causes hair follicle stem cells to activate too early, leading to hair loss.

research Depletion of Gsdma1/2/3 Alleviates PMA-Induced Epidermal Hyperplasia by Inhibiting the EGFR–Stat3/Akt Pathway

6 citations , December 2023 in “Journal of Molecular Cell Biology”

Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.

research Roles of GasderminA3 in Catagen–Telogen Transition During Hair Cycling

25 citations , April 2015 in “Journal of Investigative Dermatology”

GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.

research An Overview of Alopecias

53 citations , March 2014 in “Cold Spring Harbor Perspectives in Medicine”

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

View more "gasdermin a3" in research →

Community Join

0 / 0 results

— no results