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    Glossary Gasdermin A3

    protein crucial for hair follicle development and growth

    Gasdermin A3 is a protein that plays a crucial role in the regulation of hair follicle development and hair growth. It is part of the gasdermin family, which is involved in cell differentiation and apoptosis (programmed cell death). Mutations or dysregulation of Gasdermin A3 can lead to hair disorders, such as alopecia, where hair loss occurs due to the disruption of normal hair follicle function.

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    Research 30 of 107

    1. N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting Journal of biomedical science · 2015 · 76 citations
    2. Inducible expression of gasdermin A3 in the epidermis causes epidermal hyperplasia and skin inflammation Experimental Dermatology · 2015 · 12 citations
    3. 880 Gasdermin A3-mediated cell death causes niche collapse and precocious activation of hair follicle stem cells Journal of Investigative Dermatology · 2019 · 2 citations
    4. Roles of GasderminA3 in Catagen–Telogen Transition During Hair Cycling Journal of Investigative Dermatology · 2015 · 25 citations
    5. Depletion of <i>Gsdma1/2/3</i> alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway Journal of Molecular Cell Biology · 2023 · 6 citations
    6. Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study Current Issues in Molecular Biology · 2021 · 1 citations
    7. Effects of Acanthus ebracteatus Vahl. extract and verbascoside on human dermal papilla and murine macrophage Scientific Reports · 2022 · 7 citations
    8. Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition From Telogen to Anagen Phase Frontiers in Cell and Developmental Biology · 2022 · 5 citations
    9. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014 · 53 citations
    10. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    11. The Hair Follicle Toxicologic pathology · 2016 · 28 citations
    12. Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias Experimental Dermatology · 2018 · 22 citations
    13. Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice Acta histochemica · 2012 · 11 citations
    14. Synergistic Wound Healing: Unraveling the Multi-Target Effects of Traditional Chinese Medicine and Its Biomaterials on Chronic Wound Pathways International Journal of Nanomedicine · 2025 · 5 citations
    15. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia Archives of Dermatological Research · 2018 · 39 citations
    16. Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway Oncotarget · 2017 · 11 citations
    17. Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle Stem Cells International · 2017 · 8 citations
    18. Monoolein-alginate beads as a platform to promote adenosine cutaneous localization and wound healing International Journal of Biological Macromolecules · 2017 · 17 citations
    19. Effect of Polarized Light Therapy on Hair Regrowth in Alopecia Areata 2018
    20. Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation American Journal Of Pathology · 2011 · 54 citations
    21. Hair follicle stem cell proliferation, Akt and Wnt signaling activation in TPA-induced hair regeneration Histochemistry and Cell Biology · 2017 · 30 citations
    22. In vivo response of GsdmA3Dfl/+ mice to topically applied anti-psoriatic agents: effects on epidermal thickness, as determined by optical coherence tomography and H&E staining Experimental Dermatology · 2011 · 15 citations
    23. Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia PloS one · 2018 · 14 citations
    24. 1049 Novel strategy to promote hair follicle growth and stem cell activation in human male scalp skin: Targeting prolactin receptor with ABS-201 Journal of Investigative Dermatology · 2026
    25. 666 Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in follicular dystrophy and primary cicatricial alopecia Journal of Investigative Dermatology · 2018
    26. De novo formation and ultra-structural characterization of a fiber-producing human hair follicle equivalent in vitro Journal of biotechnology · 2011 · 44 citations
    27. Hair Follicle Stem Cells and Hair Regeneration 2020 · 3 citations
    28. Hair Follicle Stem Cells and Hair Regeneration 2020
    29. Hair follicle-specific keratins and their diseases Experimental cell research · 2007 · 138 citations
    30. A systematic summary of survival and death signalling during the life of hair follicle stem cells Stem Cell Research & Therapy · 2021 · 31 citations