Decay of Skin-Specific Gene Modules in Pangolins

    May 2023 in “ Journal of molecular evolution ”
    Bernardo Bollen Pinto, Raúl Valente, Filipe Caramelo … L. Filipe C. Castro
    Studysummary This study explored the molecular biology of skin adaptations in pangolins, revealing that certain genes for lipid synthesis have inactive patterns, while others related to skin function remain intact, suggesting complex evolutionary changes in their skin physiology.
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    Research cited in this study 6

    1. Complementary Evolution of Coding and Noncoding Sequence Underlies Mammalian Hairlessness eLife · 2022
    2. Genomic and Anatomical Comparisons of Skin Support Independent Adaptation to Life in Water by Cetaceans and Hippos Current Biology · 2021
    3. Histological Study of White Rhinoceros Integument PLoS ONE · 2017
    4. Increased Rate of Hair Keratin Gene Loss in the Cetacean Lineage BMC Genomics · 2014
    5. Immunohistochemical Demonstration of Keratins in the Epidermal Layers of the Malayan Pangolin, with Remarks on the Evolution of the Integumental Scale Armour European Journal of Histochemistry · 2013
    6. Development and Homeostasis of the Sebaceous Gland Seminars in Cell & Developmental Biology · 2012