Non-Invasive Human Skin Transcriptome Analysis Using mRNA in Skin Surface Lipids

    March 2022 in “ Communications biology ”
    Tsukasa Inoue, Tetsuya Kuwano, Yuya Uehara … Takatoshi Murase
    Studysummary In this study, researchers found that non-invasive analysis of skin surface lipid RNAs revealed alterations in gene expression patterns associated with atopic dermatitis, suggesting its potential for understanding skin disease pathophysiology.
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    Research cited in this study 8

    1. C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis Cell reports · 2013
    2. TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells BMC Dermatology · 2013
    3. The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2009
    4. Activation of Beta-Catenin Signaling Programs Embryonic Epidermis to Hair Follicle Fate Development · 2008
    5. Hair Follicle-Specific Keratins And Their Diseases Experimental cell research · 2007
    6. K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), And K28 (K25irs4) Represent The Type I Inner Root Sheath Keratins Of The Human Hair Follicle Journal of Investigative Dermatology · 2006
    7. The Role of Sebaceous Gland Activity and Scalp Microfloral Metabolism in the Etiology of Seborrheic Dermatitis and Dandruff Journal of Investigative Dermatology Symposium Proceedings · 2005
    8. Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia ˜The œAmerican journal of pathology · 2000

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