16 citations
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December 2016 in “Skin appendage disorders” This study analyzed patch test results to identify allergens causing scalp contact dermatitis, finding nickel, cobalt, and balsam of Peru among the most common in the patient population.
15 citations
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January 2020 in “ACS Applied Materials & Interfaces” This study reported that a novel chitosan/polyvinyl alcohol nanofiber sponge effectively enhances the hair follicle-inducing ability of dermal papilla multicellular spheroids in a mouse model.
13 citations
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January 2005 in “Chemical and Pharmaceutical Bulletin” This study reported that newly synthesized progesterone derivatives significantly reduced prostate weight in testosterone-treated hamsters, with 5alpha-reductase inhibitory activity dependent on the size of the substituent at C-17.
May 2023 in “International Journal of Trichology” In this study, 70% of female androgenetic alopecia patients who did not respond to standard minoxidil experienced clinical improvement after switching to a propylene glycol-free, witch hazel-based 5% minoxidil sulfate solution, with the treatment also being well-tolerated.
October 2017 in “Our Dermatology Online” This study reports that while DCP had similar treatment efficacy in propylene glycol and isopropanol for alopecia areata, the formulation in isopropanol was better tolerated.
January 2005 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” In this study, a 0.5% addition of TPGS to topical minoxidil solutions increased hair growth in mice, but higher concentrations reduced this benefit.
11 citations
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January 2016 in “Journal of clinical & experimental dermatology research” This review discusses the cutaneous manifestations associated with various substances of abuse, highlighting their importance for clinicians in recognizing and treating substance abuse disorders, and reports no new findings.
3 citations
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July 2019 in “International journal of scientific research in science and technology” This study found that a herbal gel containing fenugreek seed extract significantly promoted hair growth on mice after 30 days of topical application.
March 2002 in “Clin-Alert” In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
January 2023 in “International Journal of Trichology” This review discusses the positioning of low alcohol or alcohol-free topical minoxidil for managing androgenetic alopecia in Indian clinical practice and reports no new clinical results.
55 citations
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June 2009 in “Journal of Pharmaceutical Sciences” This study found that ethanol-containing formulations significantly increased minoxidil retention in the stratum corneum and appendages initially, while a propylene glycol-rich formulation enhanced deeper skin penetration over time.
39 citations
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April 2010 in “International Journal of Pharmaceutics” This study found that using monoolein cubic phase nanoparticles with an entrapped hydroxypropyl β-cyclodextrin/minoxidil complex increased minoxidil skin permeation, but minoxidil retention in the skin was higher with a traditional solution.
34 citations
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September 1985 in “Contact Dermatitis” Minoxidil can cause skin irritation like eczema and rash in some users.
16 citations
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August 2019 in “Cell Proliferation” This study found that 3D cultured hair follicle-like constructs, which include keratinocytes and dermal papilla cells, showed improved gene expression and cell interactions relevant to hair follicle development.
2 citations
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January 1995 in “Nihon Keshouhin Gijutsushakaishi/Journal of S C C./Nihon Keshouhin Gijutsushakai kaishi” This study found that treating permed hair with diethylene glycol monoethylether significantly reduced the formation of split ends, making it similar to untreated normal hair in terms of split ends generation.
December 2025 in “International Journal of Research in Dermatology” In this survey, dermatologists in India reported preferring alcohol-free minoxidil combined with procapil and finasteride over traditional alcohol-based formulations for managing androgenetic alopecia, citing better tolerance and patient adherence.
30 citations
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December 2019 in “PLoS ONE” This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.
1 citations
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October 2018 in “InTech eBooks” This chapter reviews ethosomes for targeted drug delivery to the scalp in androgenetic alopecia and reports no clinical results; the authors emphasize reducing systemic side effects.
26 citations
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March 2013 in “Journal of Biomedical Materials Research Part A” This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.
12 citations
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January 2018 in “Biomaterials Science” This study observed that dermal papilla cell aggregates showed increased viability and gene expression on softer 3D substrates, indicating the importance of substrate stiffness in cellular behavior.
8 citations
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July 2017 in “Biochemical and biophysical research communications” This study reported that the pseudoceramide bis-oleamido isopropyl alcohol (BOI) promotes hair growth in ex vivo cultured human hair follicles, likely by enhancing sphingolipid synthesis in dermal papilla cells.
October 2025 in “Advanced Healthcare Materials” In a study on wound healing, researchers described injectable POEGMA‐DA hydrogels as a promising non-toxic alternative to traditional wound closure methods, showing effective tissue adhesion and enhanced regeneration of skin structures in a mouse model without significant inflammation.
February 2024 in “International Journal of Research in Dermatology” In this study, alcohol-free minoxidil 5% demonstrated effectiveness in improving hair growth parameters and demonstrated a good safety profile and high patient acceptance among Indian men with androgenetic alopecia over 180 days, without any reported adverse events.
4 citations
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January 2009 in “International journal of trichology” Minoxidil topical foam is a better, less irritating treatment for hair loss.
In this study, a 34-year-old male developed allergic contact dermatitis on the scalp after using minoxidil solution for androgenic alopecia, with the reaction potentially linked to the propylene glycol in the product.
36 citations
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July 2017 in “Journal of controlled release” In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.
7 citations
,
January 2021 in “Cureus” This case report describes a 27-year-old woman who experienced facial swelling due to allergic contact dermatitis from using minoxidil 5% foam.
May 2023 in “Materials research foundations” The researchers highlighted that using nanomaterials for wound care could significantly improve healing by delivering antibacterial, antifungal, and anti-inflammatory effects, and may potentially reduce the economic burden associated with wound treatment.
July 2023 in “Journal of exploratory research in pharmacology” In this case report, a 47-year-old man with extensive psoriasis saw significant improvement in scaling and itching after using a new lotion containing clobetasol and other ingredients for one week, but further research is needed to confirm these findings.
71 citations
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September 2013 in “Materials Science and Engineering C” Keratin-based hydrogels from human hair and wool are promising for wound dressings and are more eco-friendly.