18 citations
,
July 2016 in “Journal of The American Academy of Dermatology” This study reported that both primary and secondary cutaneous follicle center lymphomas can present with atypical scalp or forehead lesions, leading to potential misdiagnosis as other skin conditions.
16 citations
,
November 2020 in “International journal of pharmaceutics” This study found that PEGylation of nanoparticles enhances their penetration into hair follicles, with higher molecular weight PEG resulting in deeper follicular delivery.
16 citations
,
April 2016 in “PLoS ONE” In a porcine model, this study observed that using an External Tissue Expansion Device increased epidermis thickness, cell proliferation, and vessel density at fat graft recipient sites.
15 citations
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December 2015 in “PLoS ONE” This study found that human adult dermal fibroblasts can express markers typically associated with neural cells, suggesting potential pitfalls in relying on immunophenotyping alone for cell identity verification.
14 citations
,
October 2016 in “Psychoneuroendocrinology” This study identified significant changes in the expression of nine proteins in the nucleus accumbens of rats treated with finasteride, suggesting potential novel targets for its neuropsychiatric effects.
14 citations
,
December 2007 in “Pediatric allergy and immunology” In this study, researchers found that mast cells in Erythema Toxicum lesions in newborns are actively involved in the immune response around hair follicles, but do not express the antimicrobial peptide LL-37.
12 citations
,
September 2021 in “PLoS ONE” In this study, researchers found that interaction between transcription factor EBF1 and gene WNT10A, influenced by a genetic variant, may play a role in hair shaft formation and anagen shortening in male pattern baldness.
12 citations
,
February 2019 in “Skin research and technology” This study found that white hair fibers have lower lipid content and different water absorption dynamics compared to brown hair fibers, suggesting differences in their barrier functions.
10 citations
,
January 2010 in “Acta Histochemica Et Cytochemica” This study found that patients with alopecia areata and androgenetic alopecia showed increased c-kit expression and decreased Ki-67 expression in hair follicle cells compared to controls, suggesting a possible feedback mechanism involving stem cell factor signaling.
9 citations
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November 2019 in “Cell calcium” This study found that a mutation causing Stormorken syndrome in mice led to skeletal abnormalities and unusual hair growth, showcasing the STIM1 R304W protein’s role in bone development and cell fate.
6 citations
,
January 2013 This chapter reviews hyperadrenocorticism in ferrets, covering its causes, symptoms, diagnosis, and treatment options, but reports no new research findings.
5 citations
,
January 2020 in “Skin Research and Technology” This study reported that combined oral finasteride and topical 5% minoxidil treatment in men with male-pattern hair loss improved hair growth by initiating anagen in pre-existing but deficient follicles, yet the growth rates remained unchanged and did not normalize hair productivity.
5 citations
,
April 2005 in “Journal of applied polymer science” This study demonstrated that urea significantly accelerates the diffusion of poly(ethylene imine) into bleached human hair by increasing the diffusion coefficient twofold.
4 citations
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February 2020 in “Cell & tissue research/Cell and tissue research” This study suggests that adult hair follicle stem cells can survive and potentially differentiate into neuronal cells after being transplanted in a mouse model of traumatic brain injury, indicating promise for TBI therapy.
3 citations
,
August 2018 in “Deleted Journal” This study found that Guasha therapy did not significantly alter nerve fiber morphology or the expression of CGRP and SP in rat skin, with parameters generally returning to normal within five days.
1 citations
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May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that ulcerative colitis is associated with diverse molecular changes and chronic inflammation, with some biomarker levels partially recovering during remission.
This study found that inhibiting the Mitochondrial Pyruvate Carrier in human scalp hair follicles caused metabolic stress that halted cell proliferation and disrupted key signaling pathways, with these effects partially reversed by an integrated stress response inhibitor.
June 2024 in “Frontiers in pharmacology” This study found that a 2-deoxy-D-ribose gel stimulated hair follicle growth in mice with androgenic alopecia, showing effects similar to minoxidil without additional benefits from combining the two treatments.
May 2021 in “Boletín latinoamericano y del Caribe de plantas medicinales y aromáticas” This study found that ethanolic extracts of Microsechium helleri showed notable antioxidant, hypoglycemic, and cardioprotective activities, while chloroformic extracts exhibited significant anti-inflammatory effects in experimental models.
This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.
December 2019 in “Ukrainian Journal of Veterinary and Agricultural Sciences” This study found that examining the microscopic and ultramicroscopic structures of donkey and horse hair can help differentiate between the species based on distinct differences in hair cuticle and brain substance patterns.
This thesis explores how optical coherence tomography and advanced imaging methods may address clinical needs in fields like interventional pulmonology and dermatology, highlighting their potential for disease assessment and staging.
May 2016 in “Research opinions in animal & veterinary sciences” In this study, aspartame consumption during gestation in rats was associated with significant histological changes and increased apoptosis in the skin of their neonatal pups.
5 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.
77 citations
,
October 2007 in “International Journal of Andrology” This study found that testosterone replacement, with or without finasteride, did not lead to significant cognitive improvements over 36 months in healthy older men without prior cognitive impairment.
75 citations
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March 1999 in “Fertility and sterility” This study concluded that finasteride, cyproterone acetate, and flutamide were similarly effective at reducing hirsutism in women, though they acted through different mechanisms.
62 citations
,
October 2010 in “Journal of biomedical nanotechnology” This review discusses the challenges and contradictions in understanding nanoparticle penetration and toxicity in human skin, emphasizing the need for standardized testing and further research on particles smaller than 10 nm.
36 citations
,
March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
25 citations
,
June 1990 in “Journal of Pharmaceutical Sciences” This study found that minoxidil absorption through the skin increased with longer contact times, reaching over 75% of the maximum absorption within four hours.
24 citations
,
May 2019 in “PLOS genetics” This study reports that compound heterozygous loss-of-function mutations in the HEPHL1 gene in a child were associated with abnormal hair and cognitive issues, linking altered ferroxidase activity to hair disorders.