research Primary Cicatricial Alopecia: Recent Advances in Understanding and Management
New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
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research Current and Potential Agents for the Treatment of Alopecia Areata
Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.
research FOXN1 Deficient Nude Severe Combined Immunodeficiency
FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
research Developing Stratified Epithelia: Lessons from the Epidermis and Thymus
The skin and thymus develop similarly to protect and support immunity.
research Hydrogel from Acellular Porcine Adipose Tissue Accelerates Wound Healing by Inducing Intradermal Adipocyte Regeneration
A hydrogel made from pig fat helps wounds heal faster by regenerating skin fat cells.
research Wnt1a Maintains Characteristics of Dermal Papilla Cells That Induce Mouse Hair Regeneration in a 3D Preculture System
Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.
research Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life
Male hormones cause different growth in identical human hair follicles due to their unique epigenetic characteristics.
research The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region and Hair Bulb Area in Chronic Alopecia Areata Patients
Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
research Biological Significance of FoxN1 Gain-of-Function Mutations During T and B Lymphopoiesis in Juvenile Mice
FoxN1 overexpression in young mice harms immune cell and skin development.
research New Pharmaceutical Concepts for Sebaceous Gland Diseases: Implementing Today's Pre-Clinical Data into Tomorrow's Daily Clinical Practice
New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
research Stem Cell Competition for Niche Occupancy: Emerging Themes and Mechanisms
Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.
research Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq
WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.
research Feather on the Cap of Medicine
Feathers are useful for researching growth, regeneration, and the effects of treatments like chemotherapy on hair loss.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research Mapping the Molecular and Structural Specialization of the Skin Basement Membrane for Inter-Tissue Interactions
The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
research Stem Cells as a Target for the Delivery of Active Molecules to Skin by Topical Administration
Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
research Cytokine-Targeted Treatment in Alopecia Areata - New Possibilities?
New cytokine-targeted therapies show promise for treating alopecia areata.
research The Role of Lipids in Promoting Hair Growth Through HIF-1 Signaling Pathway
Lipids may help treat hair loss by promoting hair growth through the HIF-1 pathway.
research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing
Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Treatment Outcome of Liquid Nitrogen Cryotherapy in Patients Presenting Recalcitrant Alopecia Areata at Tertiary Care Hospital, Karachi
Liquid nitrogen cryotherapy worked well for many patients with stubborn alopecia areata.
research Unique Treatment for Alopecia Areata Combining Epinephrine With an Intralesional Steroid
Combining epinephrine with a steroid may help regrow hair in severe alopecia areata cases.
research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis
High TSPEAR levels in colorectal cancer predict worse outcomes.
research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis
High TSPEAR levels in colorectal cancer predict worse outcomes.
research Stem Cells Sheltered from Air-Raids Repair Airways
Myoepithelial cells can repair airways after severe injury.
research Mechanisms Regulating Skin Immunity and Inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Stem cells are crucial for skin repair and new treatments for chronic wounds.
research Epidermal Stem Cell Diversity and Quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research Cartilage to Bone Transformation During Fracture Healing Is Coordinated by the Invading Vasculature and Induction of the Core Pluripotency Genes
Blood vessels and specific genes help turn cartilage into bone when bones heal.
research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.