Biological Significance of FoxN1 Gain-of-Function Mutations During T and B Lymphopoiesis in Juvenile Mice

    October 2014 in “ Cell death and disease ”
    Linhui Ruan, Z. Zhang, Lili Mu … D-M Su
    Studysummary This study found that over- and ectopic-expression of FoxN1 in early life negatively affected the development of thymic epithelial cells, T and B cells, and skin epithelial cells.
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    Research cited in this study 5

    1. Human Clinical Phenotype Associated With FOXN1 Mutations Advances in experimental medicine and biology · 2009
    2. Epithelial Stem Cells: Turning Over New Leaves Cell · 2007
    3. Learning From Nudity: Lessons From The Nude Phenotype Experimental Dermatology · 2005
    4. The Nude Gene and the Skin Experimental Dermatology · 2001
    5. Ectopic Expression of the Nude Gene Induces Hyperproliferation and Defects in Differentiation: Implications for the Self-Renewal of Cutaneous Epithelia Developmental biology · 1999