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Research

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research Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice

16 citations , October 2014 in “Cell death and disease”

This study found that over- and ectopic-expression of FoxN1 in early life negatively affected the development of thymic epithelial cells, T and B cells, and skin epithelial cells.

research Over-, ectopic-expression of FoxN1 at early life adversely influences lymphopoiesis (HEM3P.280)

May 2014 in “The journal of immunology/The Journal of immunology”

In this study, over-expression of FoxN1 in early life was associated with detrimental effects on thymic and skin epithelial development in mice.

research Thymic Stromal Lymphopoietin in Cutaneous Immune-Mediated Diseases

28 citations , June 2021 in “Frontiers in immunology”

This review discusses the role of the long form of thymic stromal lymphopoietin in cutaneous immune-mediated diseases and reports no new results.

research Adipose tissue remodeling via TSLP-mediated IL-4/IL-13 signaling: Implications for atopic dermatitis and skin barrier

June 2024 in “Journal of Allergy and Clinical Immunology”

In this study, thymic stromal lymphopoietin (TSLP) induced IL-4/IL-13 from T cells, prompting sebum secretion and adipose loss, suggesting IL-4/IL-13 may affect skin barrier function in atopic dermatitis.

Greasy Hair Against Obesity: TSLP-Induced Sebum Production Reduces Fat

research Greasy hair against obesity

December 2021 in “Signal transduction and targeted therapy”

This study found that serum levels of NF-L and GFAP decreased but tau protein levels did not change in anorexia nervosa patients after short-term partial weight restoration.

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Community Join

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community Don’t wait around, take action now.

452 upvotes 1 month ago

The user shared their positive experience with hair regrowth using minoxidil, finasteride, and ketoconazole shampoo, alongside lifestyle changes like a healthy diet and exercise. They emphasized the importance of starting treatment early and staying consistent.

community Don’t neglect your scalp health guys

112 upvotes 3 months ago

Improving scalp health can significantly impact hair loss treatment effectiveness. Using ketoconazole shampoo to reduce inflammation and dandruff can enhance the results of treatments like Dutasteride and Minoxidil.

community Doesn't feel like there's any good options (Rant)

in Chat 17 upvotes 4 months ago

An 18-year-old is experiencing significant hair loss and is concerned about treatment options, including finasteride, minoxidil, and dutasteride, due to potential side effects and costs. They are also taking vitamins for deficiencies and considering alternatives like hair transplants or embracing the bald look.

community Don't be inconsistent with Minoxidil, you will lose progress fast. My new plan for future.

161 upvotes 4 months ago

Inconsistent minoxidil use led to hair loss, prompting a plan to resume consistent application with derma stamping, red light therapy, and DHT blockers like clascoterone or RU58841. The user avoids finasteride and dutasteride due to past side effects.

community Can't help but feel somethings wrong (MtF 18)

4 upvotes 5 months ago

The user is experiencing hair loss and is using treatments like finasteride, minoxidil, and hormone replacement therapy (estradiol enanthate injections) to address it. They are advised to be patient with the treatments and consider using a dermapen for microneedling.

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Learn

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learn Dutasteride

Dutasteride: Why don't some doctors prescribe it if it's stronger than finasteride? Some doctors avoid prescribing dutasteride due to its higher risk of side effects.

learn Scalp Micropigmentation

Why can't I see my scalp micropigmentation after a week? Initial fading of scalp micropigmentation is normal and density improves with subsequent sessions.

learn Hair Transplant

What happens if I don't have enough donor hair for a hair transplant? Body hair or beard hair can be used if scalp donor hair is insufficient.

learn Centella

Ever wonder why your hair doesn’t grow back thick anymore? Maybe your scalp needs better blood flow: centella could help. There is no clinical trial of centella asiatica for hair loss and no study measuring scalp blood flow in people using it; the only hair-related evidence is a 2017 cell-culture study. Centella products are cosmetics that may soothe an irritated scalp, and the link between scalp circulation and pattern hair loss is itself unproven.

learn Redensyl

What does Redensyl do that other natural ingredients don't? Redensyl uniquely targets hair follicle stem cells to reactivate hair growth.

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