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Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.

COX2 and ATP synthase control the size of hedgehog spines.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Leptin helps start the growth phase of hair.

Hair growth genes work better with more glucose due to changes in gene-regulating markers.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

Muscles and nerves that cause goosebumps also help control hair growth.

Hydra can help understand human hair follicle microbiomes and develop new skin disease therapies.

Tetracycline can stick to hair follicles and potentially cause hair loss.

Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.

Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.

The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.

The research concluded that hyaluronic acid affects the formation and growth of hair follicle-like structures in a lab setting.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

sPLA2-IIE is crucial for normal hair follicle structure and skin health.

Medicinal herbs might treat hair loss by affecting genes and pathways related to lipid and glycerophospholipid metabolism.

The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.

Camellia japonica extract may improve scalp health and promote hair growth.

Future treatments for androgenic alopecia may focus on reactivating hair follicle stem cells and improving drug delivery.

Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.

Androgenic alopecia, a common hair loss condition, is linked to changes in androgen metabolism and genetics, and can be treated with finasteride and minoxidil, but these treatments are only fully effective in 10% of patients.

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

3D spheroid cultures of human hair follicle cells are better for hair growth research than 2D cultures, and they provide new insights into how hair growth treatments like minoxidil and TCQA work.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Communication between blood vessel and hair follicle cells decreases with age, affecting hair growth and blood vessel formation.

Testosterone is important for male sexual traits, reproduction, muscle and bone health, blood production, and metabolism, and works both directly and after being changed into other hormones.