Synergistic Antibacterial Activity and Wound Healing Properties of Selenium-Chitosan-Mupirocin Nanohybrid System: An In Vivo Study on Rat Diabetic Staphylococcus Aureus Wound Infection Model
February 2020
in “
Scientific reports
”
selenium chitosan mupirocin nanohybrid system chitosan-cetyltrimethylammonium bromide hydrogel mupirocin-methicillin-resistant Staphylococcus aureus wound healing wound contraction histopathological changes synergistic antibacterial activity minimum inhibitory concentration angiogenesis fibroblastosis collagenesis hair follicle proliferation epidermis growth SeNPs CCH MMRSA MIC
Studysummary In this study, the Selenium-Chitosan-Mupirocin nanohybrid system significantly enhanced wound healing in a rat model of diabetic wound infection compared to the control, suggesting potential for treating mild diabetic wounds.
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