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GlossaryHistopathological Changes

microscopic tissue alterations due to disease or injury

Histopathological changes refer to the microscopic alterations in tissue structure and cellular composition that occur due to disease or injury. These changes are examined through a biopsy or tissue sample under a microscope, providing crucial information for diagnosing conditions like cancer, infections, or inflammatory diseases.

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research Microneedling for Female Pattern Hair Loss: Case Report and Histopathological Changes

January 2022 in “Surgical and Cosmetic Dermatology”

A Cross-Sectional Observational Study to Correlate the Trichoscopic Findings of Female Pattern Hair Loss with the Disease Severity and Underlying Histopathological Changes

research A Cross-Sectional Observational Study to Correlate the Trichoscopic Findings of Female Pattern Hair Loss with the Disease Severity and Underlying Histopathological Changes

November 2023 in “International Journal of Trichology”

Trichoscopic features help diagnose and assess female pattern hair loss severity, with inflammation playing a key role.

research Monkeypox: A Histopathological and Transmission Electron Microscopy Study

5 citations, July 2023 in “Microorganisms”

The study found specific skin and cell changes in patients with monkeypox, helping diagnose and understand the disease.

The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen-Free Lambs Following Primary and Secondary Challenge with Orf Virus

research The Pathological Changes and Polymorphonuclear and Mast Cell Responses in the Skin of Specific Pathogen-Free Lambs Following Primary and Secondary Challenge with Orf Virus

18 citations, September 1990 in “Veterinary Dermatology”

Lambs' skin showed similar but more severe responses to a second orf virus infection, involving immune cells and new skin formation.

research Histopathological Evidence of Occipital Involvement in Male Androgenetic Alopecia

3 citations, November 2021 in “Frontiers in Medicine”

Advanced male pattern baldness affects the back of the scalp, reducing hair follicles.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community The MPB itch aka DHT itch is very real.

in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.