Atypical Presentation of Lichen Planopilaris: Presentation of Two Cases and Review

    Nwanneka Okwundu, Felicia E. Ekpo, Jessica Ghaferri, David P. Fivenson
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    TLDR Two unusual cases showed that Lichen Planopilaris can look like other skin conditions and need early treatment to protect hair.
    In 2020, two unusual cases of Lichen Planopilaris (LPP), a rare scalp disorder, were reported. The first case was diagnosed as LPP-like Folliculotropic Mycosis Fungoides due to the patient's generalized pruritus, skin eruptions, and scalp hair loss, along with biopsy findings of atypical lymphocytes and Pautrier’s microabscesses. The second case was diagnosed as an overlap of LPP and Systemic Lupus Erythematosus, as the patient had a history of the latter and presented with perifollicular erythema and alopecic patches. These cases underscored the varied presentations of LPP, which can mimic other autoimmune and non-autoimmune disorders. The study emphasized the importance of early treatment to preserve unaffected hair follicles and the need for vigilance in diagnosing new LPP patterns due to its association with other diseases.
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