2 citations
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March 2019 in “American journal of physiology. Renal physiology./American journal of physiology. Renal physiology” This paper discusses the potential of targeting fibrosis in addressing lower urinary tract symptoms associated with benign prostatic hyperplasia, but it provides no new clinical findings and highlights the need for further research.
4 citations
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June 1990 in “Postgraduate medicine” This review highlights that pharmacologic therapy for hirsutism can effectively decrease hair growth, normalize menstrual cycles, and reduce endometrial cancer risk, with improvements in physical and mental well-being and minimal serious side effects reported.
A 73-year-old woman's unusual hair loss and growth led to the discovery of a rare condition causing too much testosterone, which improved after her ovaries were removed.
2 citations
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August 2011 in “Revista Medica De Chile” This case report describes a woman with virilization syndrome who experienced a reduction in androgen levels and reversal of alopecia after removal of a Leydig cell tumor from her ovary.
10 citations
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May 1995 in “Journal of General Internal Medicine” Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
3 citations
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October 2015 in “PubMed” This study found an increased risk of intraoperative iris billowing in rabbits treated with finasteride, similar to those treated with tamsulosin, suggesting further research in humans is needed.
6 citations
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July 2013 in “Acta Clinica Belgica” This review discusses idiopathic hirsutism and suggests that combination treatment, including androgen suppression and cosmetic methods, is most effective, but notes that its pathogenesis remains unclear.
January 2007 in “Linchuang pifuke zazhi” A case study reported a 15-year-old boy with a diagnosis of giant folliculosebaceous cystic hamartoma on his right buttock, characterized by malformed hair follicles and sclerotized collagen.
May 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study describes a postmenopausal woman's diagnosis with ovarian hyperthecosis, confirmed by a GnRHa test normalizing testosterone, highlighting hormone therapy as a therapeutic option when surgery is not feasible.
April 2020 in “Journal of the Endocrine Society” This case report describes a rare occurrence of giant bilateral adrenal myelolipomas in a 28-year-old female with CAH, emphasizing that large, hormonally active, or painful myelolipomas should be surgically removed.
11 citations
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August 2019 in “PubMed” This review discusses the causes, evaluation, and treatment options for hirsutism in women, but reports no new clinical results.
33 citations
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April 2015 in “Cochrane library” This review examined various treatments for hirsutism and found low to very low quality evidence suggesting that flutamide and spironolactone may help reduce hair growth, while metformin was ineffective.
January 2017 in “University journal of surgery and surgical specialities” This case study describes a rare steroid cell tumor of the ovary in a 42-year-old woman, highlighting its virilizing effects and the importance of thorough follow-up due to its potential for malignancy.
January 2013 in “Zhonghua linchuang yishi zazhi” This study found that finasteride administration for more than one month before TURP surgery significantly reduces blood loss in patients with benign prostatic hyperplasia.
April 2024 in “International journal of reproduction, contraception, obstetrics and gynecology” This case report discusses a 17-year-old in Haiti diagnosed with a rare ovarian Sertoli-Leydig tumor, emphasizing the importance of considering future fertility and psychosocial effects when managing such conditions.
10 citations
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May 2009 in “Cases Journal” This case study reports that a virilizing Leydig cell type ovarian tumor in a 40-year-old woman caused hyperandrogenism and virilization symptoms, which improved post-surgery.
This study discusses the potential of phytochemicals, such as isoflavones and polyphenols, to manage PCOS symptoms by improving insulin resistance, regulating hormones, and reducing cyst size, highlighting their promise as alternative treatments given the limitations of current pharmacological options.
February 2010 in “Acta Obstetricia et Gynecologica Scandinavica” This collection of articles in AOGS includes findings on tetranectin as a possible prognostic marker for advanced ovarian cancer, and the effectiveness of tension-free vaginal tape for recurrent stress urinary incontinence.
In this case report, researchers detailed a giant proliferating pilomatrixoma in a 36-year-old woman, emphasizing the importance of complete excision to prevent recurrence or potential malignant transformation, distinguishing it from malignancies like angiosarcoma or melanoma.
November 2025 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” This study examined 16 sporadic trichoblastic tumors and found that although one showed malignant transformation, clinical follow-up revealed no residual or metastatic disease. RNA sequencing indicated a high tumor mutational burden and absence of a UV-related signature, helping to distinguish these tumors from similar growths.
3 citations
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July 2019 in “Case Reports in Obstetrics and Gynecology” This case report and literature review describes a 27-year-old woman with a Sertoli Leydig cell tumor causing testosterone-related symptoms and highlights normalization of hormone levels after surgical treatment.
27 citations
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April 2017 in “European journal of endocrinology” This retrospective study found that serum hormone levels and MRI detection of ovarian nodules contributed to distinguishing virilizing ovarian tumors from ovarian stromal hyperthecosis in postmenopausal women, though histopathology remains crucial for diagnosis.
2 citations
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July 2012 in “Obstetrics, gynaecology and reproductive medicine” This article reviews the physiology, causes, and treatments of hirsutism and reports no new research findings.
1 citations
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July 2006 in “Reviews in gynaecological and perinatal practice” This review explores various therapeutic options for managing female hirsutism, emphasizing the effectiveness of low-dose finasteride and cyproterone acetate, but it presents no new clinical results.
October 2024 in “Journal of the Endocrine Society” This case report describes a patient with an ovarian steroid cell tumor that initially presented as non-classical adrenal hyperplasia, emphasizing the difficulty in differential diagnosis with hyperandrogenism and the importance of close clinical monitoring.
May 2006 in “Women's Health Medicine” This review examines the causes, assessment, and treatments of hirsutism and highlights the need for future research in managing this condition but presents no new research findings.
1 citations
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December 2019 in “Medical Journal of Dr D Y Patil Vidyapeeth” This case report details a 26-year-old woman with a rare large functional adrenal myelolipoma, characterized by elevated hormone levels and requiring surgical intervention.
February 2025 in “Clinical Chemistry” This case study reported a 34-year-old woman presenting with secondary amenorrhea, hirsutism, and obesity showed elevated testosterone and anti-Müllerian hormone levels, leading to the exclusion of nonclassical congenital adrenal hyperplasia as a diagnosis.
5 citations
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October 2014 in “Gynecological Endocrinology” This case study describes a 15-year-old girl with a Sertoli–Leydig cell tumor who showed high androgen levels and steroidogenic responses similar to patients with polycystic ovary syndrome before surgery.
This study found that using fenugreek seed extract significantly reduced ovarian volume, cyst size, and prolactin levels in women with PCOS over 12 weeks, with the majority achieving regular menstrual cycles and improved insulin sensitivity.