A Rare Case of Steroid Cell Tumor, Not Otherwise Specified, of the Ovary in a Young Woman

    July 2019 in “ Case Reports in Obstetrics and Gynecology ”
    Eek Chaw Tan, Chit Chong Khong, Kazila Bhutia
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    TLDR A young woman's rare ovarian tumor was successfully removed, improving her hormonal symptoms.
    The document describes the case of a 27-year-old woman who was diagnosed with a steroid cell tumor, NOS, of the ovary after presenting with virilization symptoms for 8 years. This type of tumor is extremely rare, making up less than 0.1% of all ovarian tumors. Her symptoms included hirsutism, hoarseness, scalp hair loss, and amenorrhea. Elevated testosterone levels and an MRI revealing a left adnexal mass initially suggested a Sertoli Leydig cell tumor, but a left salpingo-oophorectomy followed by histopathological examination and immunohistochemistry confirmed it was a steroid cell tumor, NOS. After the surgery, her testosterone levels normalized within 3 days, and her menstrual cycle returned after a few months. The document also reviews related literature on the condition's epidemiology, clinical presentation, imaging and histological findings, and treatment options, emphasizing the need to consider neoplastic causes in young patients with severe virilization and menstrual irregularities.
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