Virilizing Ovarian Steroid Cell Tumor in a 40-Year-Old South Indian Female: A Case Report
May 2009
in “
Cases Journal
”
TLDR A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.
In 2009, a 40-year-old South Indian female exhibited virilization symptoms such as a deepened voice, hirsutism, clitoromegaly, and androgenic alopecia. Elevated testosterone levels and normal FSH and LH levels were found in her laboratory tests. An ovarian mass was detected through imaging, leading to a total abdominal hysterectomy with bilateral salpingoophorectomy. The histopathological examination identified a steroid-cell ovarian tumor of the Leydig cell type as the virilization source. After surgery, the patient's testosterone levels decreased, and there was a significant reversal of her symptoms, except for the deepened voice. This case underscores the need for thorough investigation in virilism cases and the success of surgical treatment in symptom management.
