The Investigation and Management of the Hirsute Woman

    Nadia Soliman, Peter G. Wardle
    TLDR The document concludes that hirsutism in women, often caused by PCOS, requires systematic evaluation and can be treated with medications, mechanical removal, or cosmetic methods, with weight loss also being beneficial.
    The document from 2006 discusses the condition of female hirsutism, which is characterized by excessive hair growth in a pattern similar to males, often due to increased androgen production or sensitivity. Polycystic ovary syndrome (PCOS) is identified as the most common cause. A systematic evaluation is necessary to identify any serious underlying causes. Treatment options include medical therapies targeting different action sites, mechanical removal, cosmetic approaches, and a topical treatment to slow hair growth. The combined oral contraceptive pill (OCP) is frequently used, but may not be suitable for obese patients. Other effective treatments mentioned are finasteride, cyproterone acetate, and spironolactone, with low doses being just as effective. Insulin sensitisers like metformin show promise, but more data is needed. Weight reduction is emphasized as an important part of treatment for overweight women. Systemic treatments are expected to show benefits after 6–12 months due to hair growth cycles. Contraception is advised during treatment to prevent harm to a male fetus. In the UK, Vaniqa and Dianette are the only licensed treatments for hirsutism.
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