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    Spironolactone Versus Placebo or in Combination with Steroids for Hirsutism and Acne

    October 2003
    Julie Brown, Cindy Farquhar, Olivia Lee … Ruth Jepson
    Studysummary This review reports that 100 mg/day spironolactone improved hair growth more than placebo and was more effective in reducing hair growth than finasteride and low-dose cyproterone acetate, but its effectiveness for acne remains unclear due to small sample sizes.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 10

    1. Lack of Effect of a Spironolactone-Containing Cream on Hair Growth in Hirsute Women Dermatology · 2009
    2. Cyproterone Acetate for Hirsutism Cochrane library · 2003
    3. Use of Cyproterone Acetate, Finasteride, and Spironolactone to Treat Idiopathic Hirsutism Fertility and Sterility · 2003
    4. Comparison of Spironolactone and Spironolactone Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2002
    5. Comparison of Spironolactone, Flutamide, and Finasteride Efficacy in the Treatment of Hirsutism: A Randomized, Double-Blind, Placebo-Controlled Trial The Journal of Clinical Endocrinology and Metabolism · 2000
    6. A Prospective Randomized Trial Comparing Finasteride to Spironolactone in the Treatment of Hirsute Women The Journal of Clinical Endocrinology and Metabolism · 1995
    7. Antiandrogens: Clinical Applications The Journal of Steroid Biochemistry and Molecular Biology · 1990
    8. Lack of Effect of Spironolactone on Hair Shaft Diameter in Hirsute Females Postgraduate medical journal · 1989
    9. Spironolactone in Combination Drug Therapy for Unresponsive Hirsutism Fertility and sterility · 1985
    10. The Effects of Two Doses of Spironolactone on Serum Androgens and Anagen Hair in Hirsute Women Fertility and sterility · 1985

    Related research 3

    1. Cutaneous Hyperandrogenism: Role of Antiandrogen Therapy in Acne, Hirsutism, and Androgenetic Alopecia PubMed · 2013
    2. Diagnosis of Hyperandrogenism: Clinical Criteria Best Practice & Research Clinical Endocrinology & Metabolism · 2006
    3. A Novel Use of Spironolactone: Treatment of Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1980