Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study suggests that human mesenchymal stem cells have the potential to differentiate into dermal papilla cells both in vitro and in vivo.

This study found that cholesterol- and phospholipid-free multilamellar niosomes improved skin deposition and targeted deeper hair follicles better than hydrophobic PLGA nanoparticles for transdermal drug delivery.

This research by Yuan et al. focused on developing a comprehensive human skin cell atlas, analyzing various cell types and diseases, and introduced a deep learning method, scSEA, for unbiased reference mapping, potentially discovering new cell types.

This study observed that topical application of palmitate or oleate accelerated the onset of the hair growth phase in mice, whereas glycolysis end product lactate delayed it, suggesting metabolic regulation as a promising approach for influencing hair growth.

Blocking the JAK/STAT pathway may help reduce skin sensitivity in Xeroderma pigmentosum.

This study developed a comprehensive atlas of human scalp tissue to uncover cell states and lineages in hair follicles, identifying disease-specific cellular changes associated with non-scarring and scarring hair loss, which may offer new diagnostic and therapeutic insights.

This review examined the pathological effects of mechanical pressure on human skin at the cellular level, highlighting how various skin cell types respond to pressure, potentially leading to pathological changes such as inflammation, ischemia, and impaired differentiation.

In this study, the combination of conditioned medium from human adipose-derived stem cells and photobiomodulation significantly enhanced wound healing in type 2 diabetic rats compared to using either treatment alone, with particularly superior results in wound strength and new blood vessel formation.

This review discusses the use of human-to-mouse xenografting to study human skin processes in vivo, highlighting its importance for understanding skin regeneration and pathology while identifying knowledge gaps and challenges in applying these findings to human skin.

FGF18 helps keep hair in its resting phase, affecting hair growth cycles.

This review discusses the multiple factors contributing to skin aging, including cellular changes and environmental influences, and highlights its recognition as a disease with significant implications beyond cosmetic concerns, without reporting new research results.

Keratin-based hydrogels from human hair improve wound healing effectively.

This review discusses the experimental targets of fetal wound healing and evaluates existing therapies for scarless healing in adult skin, but reports no new research findings.

This review discusses the role of fascial mobilization in wound healing and its potential implications for treating chronic skin wounds and scarring, but reports no new clinical results.

This review discusses skin tissue engineering and highlights the potential role of microRNAs in improving bioengineered skin equivalents, concluding that further exploration of microRNA targets could address unmet clinical needs.

This review examines the complexities of age-related skin healing and discusses how translating findings from model organisms to humans could enhance understanding and treatment of impaired regeneration in aging populations, but it reports no new clinical results.

This study found that SIRT1 negatively regulates fibroblast activation and excessive scar formation, suggesting it may be a promising drug target for treating hypertrophic scars.

This review discusses stem cell therapy as a promising treatment for epidermolysis bullosa, highlighting preliminary successes in treating skin lesions but noting the need for further research on effectiveness and safety.

This review discusses the role and interactions of the calcium-binding protein S100A6 in cellular processes and its association with various diseases, highlighting the need for further research to fully understand its biological impact.

Fibroblasts from healthy donors can prevent changes seen in recessive epidermolysis bullosa simplex.

This study found that Fibroblast growth factor-9 (FGF-9) accelerates epithelial invagination in engineered ectodermal organs and suggests its potential role in organogenesis and regeneration research.

This study demonstrated that a 3D bioprinting technique using a gelatin/alginate hydrogel scaffold can regenerate entire hair follicles in mice, offering potential advancements in hair loss treatment.

This study developed a nanoscale biomimetic matrix that effectively and stably expands human hair follicle stem cells, offering a new tool for hair follicle reconstruction research.

This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.

This study found that conditioned medium from hair dermal papilla cells stimulated fetal bovine aortic endothelial cell growth and migration, suggesting VEGF-like activity in the medium.

This study investigated a gelatin-based bioink for 3D bioprinting a simplified skin model, finding that a formulation with 15% gelatin and 150 mM calcium chloride supported a homogeneous distribution of viable cells over 14 days, showing promise for drug evaluation applications.

This review suggests that telocytes in male reproductive organs help organize tissue structure and paracrine factors, impacting organ development and pathology, but more research is needed on their molecular pathways.

This review discusses the potential of extracellular vesicles for facial aesthetic applications, including scar reduction and skin rejuvenation, but reports no new clinical results; further research into production and mechanisms is needed.

This study found that the natural extract e-CAF promotes the proliferation and migration of human hair dermal papilla cells in vitro, suggesting potential benefits for skin regeneration and tissue repair.

This review discusses the role of transient receptor potential channels in pathological scarification and suggests these channels as potential targets for its prevention and treatment, although it reports no new clinical findings.