50 citations
,
March 2021 in “Journal of investigational allergology & clinical immunology” This review examines existing research and clinical trials on the use of dupilumab for various skin, respiratory, and gastrointestinal disorders, but it reports no new clinical findings.
18 citations
,
October 2012 in “Dermatologic Clinics” This article discusses primary cicatricial alopecias, a group of rare inflammatory scalp disorders resulting in permanent hair loss, and reports no new findings.
6 citations
,
February 2022 in “The journal of neuroscience/The Journal of neuroscience” This study observed that deleting PTEN in mouse facial motoneurons enhanced peripheral axon regeneration but also led to physiological changes and potential hyperplasia in older mice.
May 2024 in “Frontiers in Immunology” In this mini-review, recent insights suggest a possible role of type-2-related immunity in diseases like alopecia areata, vitiligo, and localized scleroderma, though whether this immune response benefits or worsens these conditions remains unclear.
January 2014 in “Side effects of drugs annual” This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.
17 citations
,
June 2018 in “Frontiers in Physiology” This study found that acellular dermal matrix scaffolds may facilitate full-thickness skin wound healing by promoting a pro-regenerative immune response through M2 macrophage polarization via the Lamtor1 pathway.
15 citations
,
January 2019 in “Mediators of inflammation” This study concluded that Aloe vera fermentation significantly accelerates burn injury healing in rats by reducing inflammation and altering gut microbiota composition.
11 citations
,
June 2017 in “Journal of cell science” In this study, researchers found that AGD1 is crucial for membrane recruitment during root hair development in Arabidopsis thaliana, with its pleckstrin homology domain essential for targeting specific plasma membrane regions.
3 citations
,
April 2018 in “Holzforschung” This study identified seven compounds from Cercidiphyllum japonicum twig extracts, including a newly discovered flavonoid, marking the first time these specific compounds have been isolated from this genus.
18 citations
,
April 2016 in “Molecular Genetics and Genomics” This study suggests that thymosin beta 4 may regulate hair growth by influencing VEGF and MMP-2 levels through the Wnt/β-catenin/Lef-1 signaling pathway in mouse models.
17 citations
,
January 2019 in “International journal of biological sciences” This study found that inserting the Tβ4 gene into cashmere goats increased cashmere yield by 74.5% without compromising quality, suggesting potential economic benefits for goat breeding.
9 citations
,
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” In this study, PGD2 was shown to increase testosterone production in human keratinocytes through reactive oxygen species, suggesting potential benefits of antioxidants like N-acetyl-cysteine for AGA patients.
July 2021 in “Advances in laboratory medicine” This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.
44 citations
,
April 2003 in “European journal of pharmaceutical sciences” This study found that targeting the hair follicle can be increased by using lipophilic drugs combined with surfactant solutions and propylene glycol.
July 2022 in “Biomedicines” This study found that 4-aminopyridine significantly enhanced skin wound healing by accelerating wound closure, improving skin architecture, and promoting hair follicle neogenesis and tissue regeneration.
28 citations
,
November 2013 in “Cell and Tissue Research”
13 citations
,
March 2020 in “Genes” This study found that FGF5-/- rabbits exhibited a significant long hair phenotype by prolonging the anagen phase, suggesting FGF5 acts as a negative regulator of hair growth.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified a gene regulatory network in Arabidopsis that controls root hair growth under low-temperature conditions, revealing specific transcription factors and downstream targets that contribute to this growth response despite overall plant development being halted.
5 citations
,
July 2022 in “Orphanet journal of rare diseases” This study found that RSPO1 mutations in patients with a 46XX disorder of sexual development contribute to impaired skin integrity and increased risk of squamous cell carcinoma in areas subject to friction.
1 citations
,
February 2023 in “Plants” This study reported that rice bran oil from the Thai rice variety BB4CMU showed potential in promoting melanin production and inhibiting steroid 5α-reductase, suggesting a natural option for hair revitalization.
December 2022 in “Clinical and experimental dermatology and therapies” In this study, the addition of a topical gel containing growth-factor mimicking oligopeptides and other ingredients showed improved efficacy in subjects with androgenic alopecia using minoxidil or finasteride compared to drug treatment alone.
203 citations
,
May 2022 in “Pharmaceutics” This review discusses ongoing concerns and advancements in the use of gelatin as a biomaterial in tissue engineering, highlighting improved tissue mimicry through techniques like 3D bioprinting and suggesting a future focus on disease detection and diagnosis rather than treatment.
2 citations
,
April 2023 in “Polymers” This study explored the creation of 3D-printed baricitinib pills using polylactic acid and found that the doughnut-shaped tablets increased surface area and drug release, with 59% released from the higher concentration pill over 24 hours.
2 citations
,
December 2020 in “JAMA Dermatology” In this study, the incidence of androgenic alopecia among transgender patients increased after starting masculinizing hormone therapy, with the highest incidence observed in the fourth year of treatment.
43 citations
,
January 2015 in “Journal of Cutaneous Medicine and Surgery” This study found that most patients with folliculitis decalvans showed improvement and remission with oral antibiotics, although some experienced relapses and required prolonged treatment.
1 citations
,
November 2022 in “International journal of molecular sciences” This study found that local injections of fetal tissue mesenchymal stromal cells in mice significantly improved healing and hair follicle density after high-dose radiation-induced skin damage.
132 citations
,
June 2016 in “Cell and Tissue Research” This review discusses recent advancements in scar reduction techniques, highlighting promising therapeutic targets and the role of Wnt/β-catenin signaling in promoting scarless wound healing, but reports no new clinical results.
26 citations
,
January 2018 in “Skin appendage disorders” This review summarizes existing studies on toxic agents that can cause alopecia, with thallium and colchicine having the most established links, while others like botulinum toxin A need further investigation.
January 2022 in “Clinical Cases in Dermatology” This article discusses the etiology, clinical presentation, and current treatment options for alopecia areata and highlights new therapeutic modalities under investigation, but it reports no new research results.
3 citations
,
July 2023 in “Biomolecules” This study reports that some human cell surface HLA-I molecules (including HLA-B27) can appear without their usual peptide component, potentially altering immune interactions, influencing arthritis development in specific mice models, and exhibiting upregulation in certain cancer cells.