Postoperative Radiotherapy for Cutaneous Squamous Cell Carcinoma in Patients With Microscopic Residual Disease

    December 2020 in “ JAMA Dermatology ”
    Alet J G Leus, Estelle F D Perrels, György B. Halmos, Jorrit B. Terra, Roel J.H.M. Steenbakkers, Marloes S. van Kester, Emőke Rácz
    Image of study
    TLDR Radiotherapy is a good option when further surgery for skin cancer isn't preferred, but more research is needed to compare it with other methods.
    This case series examined the outcomes of postoperative radiotherapy (PORT) in 66 patients with microscopic residual disease from cutaneous squamous cell carcinoma. The patients were diagnosed between January 1, 2000, and January 1, 2014, and treated with PORT following incomplete excision. The median follow-up was 45.5 months. Thirteen patients (19.7%) developed progression of disease (POD), including local recurrence, nodal metastasis, and disease-specific death. The median time until POD was 15 months, and the median disease-free survival in the total group was 44 months. The study concluded that PORT after incomplete excision is a good treatment option if reexcision of the tumor is not preferable. However, additional comparative studies are necessary to determine the value of PORT compared with reexcision or watchful waiting.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 19 results

      community Scientific evidence for Peppermint & Rosemary oils + My Experience

      in Research/Science  114 upvotes 3 years ago
      Natural treatments for hair loss, specifically peppermint oil and rosemary oil; how they can be used as a supplementary or alternative treatment to pharmaceuticals such as finasteride and minoxidil; and the personal experience of the user Divallo, who has seen an increase in density and thickness after using these oils for around 2.5 years. The post also touches on the potential antifungal properties of the oils and their effects on cutaneous blood flow.

      community Not sure if fin is enough, still losing lots of hair

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The user has been on finasteride for 17 months to treat hair loss, with some improvement in the crown but still experiencing significant shedding. They are considering if finasteride alone is sufficient and are hesitant to use minoxidil due to a pre-existing condition, while another person suggests trying dutasteride.

      community How do you use rosemary oil and peppermint oil?

      in Question  7 upvotes 6 years ago
      Rosemary oil and peppermint oil may promote hair growth and increase cutaneous blood flow, showing promise as treatments for androgenetic alopecia. Minoxidil 2% is also used for treating hair loss.

      community high bloodpressure and crown thinning in early 20s

      in Is this regrowth?  9 upvotes 1 year ago
      A user with kidney disease and high blood pressure experienced hair thinning, especially around the vertex. They are currently using finasteride and oral minoxidil but are considering whether to resume blood pressure medication despite managing symptoms with diet and exercise.

    Similar Research

    5 / 1000+ results